Products

1-(4-Fluorophenyl) piperazine dihydrochloride, inozivikanwawo se 4-FPP, ikemikari inosanganiswa inowana kushandiswa kwakasiyana-siyana muminda yemishonga nekutsvakurudza.Yayo yakasiyana-siyana yemamolecular chimiro ine fluorine atomu uye piperazine mhete inoita kuti ive yakakosha kune zvinangwa zvakasiyana-siyana, kubva pakugadzirwa kwezvinodhaka kusvika pakuferefetwa kwesainzi. mishonga yakawanda yekurapa.Nekuda kwekugona kwayo kuita shanduko yemakemikari, inogonesa kugadzirwa kwevanoda zvinodhaka vanokwanisa kuita zvemishonga.Kuvapo kwepiperazine moiety muhutano hwayo inonyanya kubatsira pakugadzirwa kwemishonga inotarisa pakati penheyo system, yakadai se antipsychotics, antidepressants, uye anti-anxiety agents. Uyezve, 1-(4-Fluorophenyl) piperazine dihydrochloride inowanzoshandiswa mu tsvagiridzo yesainzi yekuongorora akasiyana maitiro ebhayoloji.Semamorekuru echishandiso anochinja-chinja, anoshandiswa kudzidza kusungirirwa kwekugamuchira, kupindirana kweurourochemical, uye mhedzisiro yemishonga pane chaiwo masisitimu emuviri.Vatsvagiri vanoshandisa iyi kompani kuburitsa nzira dzekuita kwemishonga yakasiyana, kujekesa receptor subtypes, uye kuongorora nzira dzekufambisa dzechiratidzo.Nekuwana kunzwisisa kwakadzama kwemaitiro aya, masayendisiti anogona kufambisira mberi ruzivo rwakatenderedza huwandu hwezvirwere zvetsinga uye zvepfungwa, zvichigadzira nzira yekuvandudzwa kwemaitiro matsva ekurapa. Uyezve, 1-(4-Fluorophenyl) piperazine dihydrochloride inoshandiswa sechinhu chakakosha chepakutanga iyo synthesis ye radioligands ye positron emission tomography (PET).MaRadioligands akavakirwa pane iyi komputa, yakanyorwa neradioactive isotopes, inobvumira iyo isiri-invasive yekuona uye kuwanda kweiyo chaiyo biochemical maitiro mumuviri wemunhu.Maitiro akadaro ekufungidzira anopa ruzivo rwakakosha mukugoverwa kwekugamuchira, kugara, uye kuwanda, kubatsira mukutsvagisa mamiriro akasiyana-siyana etsinga uye kubatsira mukukudziridza nzira dzakanangwa dzekurapa.Zvakakosha kubata 1-(4-Fluorophenyl)piperazine dihydrochloride nekuchenjerera, sezvo ichionekwa sechinhu chinogona kuva nengozi.Matanho akakodzera ekuchengetedza uye midziyo yekuzvidzivirira inofanira kushandiswa kuderedza njodzi yekusangana netsaona kana kubatwa zvisina kunaka.Muchidimbu, 1-(4-Fluorophenyl)piperazine dihydrochloride musanganiswa unoshandiswa muzvikamu zvemishonga netsvakurudzo.Zvishandiso zvaro zvinosanganisira synthesis yezvinodhaka, kudzidza kwebiological process, uye kuvandudzwa kweradioligands yePET imaging.Zivo yezvimiro zvekomboni uye kubata zvine hungwaru kwakakosha kuti uve nechokwadi chekuchengetedzwa uye kufambisa mipiro yayo yakakosha mukusimudzira sainzi nemishonga.