1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas:41575-94-4
| Catalog Number | XD90684 |
| Product Name | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
| CAS | 41575-94-4 |
| Molecular Formula | C6H12N2O4Pt |
| Molecular Weight | 371.25 |
| Storage Details | 2-8°C |
| Harmonised Tariff Code | 28439090 |
Chigadzirwa Specification
| Chitarisiko | Hupfu hwakachena kusvika kuchena |
| Assay | 99% |
| Mvura | ≤0.5% |
| Kurasika paKuomesa | ≤0.5% |
| Chlorides | ≤100ppm |
| Related Substances | ≤0.25% |
| Chero Kusachena Kusina Kutaurwa | ≤ 0.1% |
| Zvimwe zvitsvina zvese | ≤0.5% |
| 1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
Chechipiri-chizvarwa platinum yakaoma antineoplastic mishonga.Iyo antitumor spectrum uye antitumor chiitiko chakafanana neye cisplatin, asi kunyungudika kwemvura kuri nani pane kwecisplatin, uye chepfu kuitsvo zvakare yakaderera.Iine kurapa kwakanaka kwekenza yemapapu diki, kenza yeovarian, musoro nemutsipa squamous cell carcinoma, testicular bundu, malignant lymphoma, etc. Inogona zvakare kushandiswa kugomarara remuchibereko, dundira, nezvimwe.
Yechipiri-chizvarwa platinum anticancer mishonga ine basa rakafanana uye rinoshandisa se cisplatin.Inoshanda kupfuura cisplatin kune mamwe mamota, uye yakasimba kudarika cisplatin seradiosensitizer pasi pe hypoxic conditions.Inonyanya kushandiswa kwegomarara reovarian, testicular cancer, kenza diki yemapapu uye musoro nemutsipa.
Carboplatin iplatinum-based anticancer drug inokuvadza DNA nekugadzira intrachain conjugation kune iri padyo nemasara eguanine.Iyo antitumor effect yemishonga iyi inowanikwa nekurasikirwa kweDNA mismatch repair (MMR vaccine) chiitiko uye induction ye programmed cell death.
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