Products

(1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane-2-carboxylic acid Methyl ester hydrochloride ikemikari inosanganiswa nemhando dzakasiyana-siyana mukutsvakurudza kwemishonga uye kukura kwezvinodhaka. mashandisirwo akakosha emushonga uyu sechiral chivakwa chekuvaka mukugadzirisa kwemishonga yepakati uye inoshanda yemishonga yemishonga (APIs).Yayo yakasiyana bhicyclic chimiro uye chirality inoita kuti ive yakakosha mukugadzirwa kweenantiomerically yakachena makomisheni.Nekubatanidza iyi komisheni mune synthesis, chemist inogona kudzora stereochemistry uye kugadzira chaiyo yemishonga zvimiro mumamorekuru anokonzeresa.Izvi zvinonyanya kukosha mukugadzirwa kwezvinodhaka, uko kudiwa kwehupenyu hwehupenyu hunowanzoenderana nekurongeka kwenzvimbo yemorekuru.Kuwedzera, (1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane -2-carboxylic acid Methyl ester hydrochloride inoshandiswa sechigadziro chekugadzirisa kwemishonga yequinuclidine-based.Zvinyorwa zveQuinuclidine zvakaratidza kuwanda kwezviitiko zvehupenyu, kusanganisira antipsychotic, anticonvulsant, uye analgesic properties.Nekuunza chaiwo mapoka anoshanda kune iyo komputa, chemist inogona kushandura iyo pharmacokinetic uye pharmacodynamic maitiro, ichiwedzera ayo ekurapa kugona.Uyezve, iyi komputa inowana kushandiswa seyakagadziriswa kana inokonzeresa mune organic shanduko.Nekuda kwekuvapo kweamine yepamusoro uye nekudzivirirwa kwakasimba kwemapoka emethyl, inogona kutora chikamu mune akasiyana makemikari maitiro, senge amidation, alkylation, uye cycloaddition reactions.Kudzokorora kwayo uye kukwanisa kuumba midzi yakaoma inoita kuti ive chimbo chakasiyana-siyana mune organic synthesis, inobvumira kugadzirwa kwezvakasiyana-siyana zvemakomisheni.Muchidimbu, (1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1 .0]hexane-2-carboxylic acid Methyl ester hydrochloride chinhu chakakosha mukugadzirwa kwezvinodhaka uye organic synthesis.Hunhu hwayo uye chimiro chakasarudzika chinogonesa kugadzirwa kweenantiomerically yakachena komisheni uye synthesis yequinuclidine-yakavakirwa mishonga ine chaiyo pharmacological properties.Reactivity yayo inoitawo kuti ive inobatsira reactant uye catalyst mune akasiyana makemikari shanduko.Pakazere, komisheni iyi inoita basa rakakosha mukufambisira mberi kwetsvakiridzo yemishonga uye kuvandudzwa kwemishonga mitsva yekurapa.