Products

Mushonga 2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1, 3 (2H) -dione yakaoma organic molecule ine zvinogona kushandiswa muminda yemishonga nemishonga.Kuvapo kweiyo isoindole core kunoratidza kuti komisheni iyi ine zvimiro zvemuviri zvinoenderana nehupenyu uye zvakawanikwa mune bioactive molecules.Isoindole derivatives inonzi ine zvinhu zvakasiyana-siyana zvemishonga, kusanganisira antitumor, anti-inflammatory, uye antimicrobial activities.Iyo oxazolidinone moiety, inomiririrwa neboka re1,3-oxazolidin-5-yl, inozivikanwa nokuda kwekuita kwayo antibacterial.Oxazolidinones yakashandiswa sezvikamu zvakakosha mumishonga inorwisa mabhakitiriya, kunyanya kurwisa mabhakitiriya asingaurayiwi nemishonga.Izvi zvinoratidza kuti musanganiswa unogona kuva nekwanisi sechinhu chinorwisa mabhakitiriya.Kuvapo kwemorpholinone moiety, inomiririrwa neboka re4-(3-oxomorpholin-4-yl) phenyl, rinowedzera humwe hunyoro kune zvinogona kushandiswa kwekomboni.Morpholines yakaverengerwa zvakanyanya mumisanganiswa yemishonga nekuda kwekugona kwavo kupindirana neakasiyana siyana ehupenyu.Boka reoxo riri pamorpholinone rinogona kuwedzera kudyidzana kwekomboni nezvinangwa chaizvo, zvichiita kuti ive chivako chakakosha pakuwana zvinodhaka nekuvandudzwa.The 2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]- 1,3-oxazolidin-5-yl boka, rakabatanidzwa kune isoindole core, rinoumba nzvimbo huru inoshanda yekomboni.Chimiro chemakemikari eboka iri chinoratidza kuti inogona kunge iine kudyidzana nezvinangwa zvehupenyu zvakadai sema enzymes kana receptors.Pasese, zvichienderana nemaitiro emukomboni, ane mukana wekuratidzira mabasa emishonga mune antibacterial, anti-inflammatory, uye dzimwe nzvimbo dzinogona kurapa.Nekudaro, mashandisirwo ayo chaiwo uye maitiro echiito angada kutariswa kuburikidza nezvimwe zvidzidzo, zvinosanganisira in vitro uye in vivo kuyedza, kuongorora kushanda kwayo uye kuchengetedzwa profiles. -3--[4-(3-oxomorpholin-4-yl) phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione inoratidza chivimbiso muminda yemishonga. uye mishonga nekuda kwechimiro chayo chakaoma uye chinogona kuitika chemishonga.Tsvagiridzo yeramangwana inodiwa kuti uongorore mashandisiro ayo chaiwo, zvingangove zvekurapa zvikumbiro, uye kushanda kwese.