3-tert-Butoxycarbonylphenylboronic acid CAS: 220210-56-0
Catalog Number | XD93445 |
Product Name | 3-tert-Butoxycarbonylphenylboronic acid |
CAS | 220210-56-0 |
Molecular Formula | C11H15BO4 |
Molecular Weight | 222.05 |
Storage Details | Ambient |
Chigadzirwa Specification
Chitarisiko | Upfu chena |
Assay | 99% min |
3-tert-Butoxycarbonylphenylboronic acid, inozivikanwawo seBoc-phenylboronic acid, yakakosha boronic acid kubva kune yakakosha maapplication mu organic synthesis uye chemistry yemishonga.Imwe yekutanga kushandiswa kwe3-tert-Butoxycarbonylphenylboronic acid iboka rinodzivirira mune organic. synthesis.Boka re tert-butyloxycarbonyl (BOC) rinowanzo shandiswa kuchengetedza kwenguva pfupi mapoka anoshanda emamine panguva dzakasiyana siyana.Nekubatanidza boka reBOC kune amine moiety, reactivity yeamine inoderedzwa, ichibvumira maitiro ekusarudza pane dzimwe nzvimbo pane molecule.Boka reBOC rinogona kubviswa zviri nyore pasi pemamiriro akapfava, nekudaro zvichiburitsa mashandiro ekutanga amine.Iri sangano rekudzivirira boka rinogonesa kushandiswa kwakanaka kwema molecules akaoma, akadai semishonga uye zvigadzirwa zvepanyama.Uyezve, 3-tert-Butoxycarbonylphenylboronic acid inoshanda sechinhu chakakosha reagent ye carbon-carbon bond formation.Boronic acids, kusanganisira Boc-phenylboronic acid, inogadzira boronate esters kana yaitwa nucleophiles, yakadai sedoro kana amines.Aya boronate esters anogona kubva aita shanduko dzakasiyana, kusanganisira Suzuki-Miyaura cross-coupling reactions, Negishi couplings, uye Stille couplings.Aya maitiro anogonesa kuumbwa kweakaomesesa organic mamorekuru ane akasiyana ekutsiva mapatani uye anoshanda mapoka.Boc-phenylboronic acid inonyanya kubatsira pakuunza iyo phenylboronic acid moiety mumamorekuru anonangwa. Pamusoro pazvo, Boc-phenylboronic acid inoita basa rakakosha mumakemikari ekurapa.Iyo boronic acid mashandiro anogona kusarudza kudyidzana nema diols kana boronate ester-sensitive anoshanda mapoka mune biological zvinangwa, zvichigonesa dhizaini yeboronate-based enzyme inhibitors uye receptor ligands.Boc-phenylboronic acid inogona kuiswa mune diki-morekuru inhibitors, peptides, kana maprodrugs kuti ape anodiwa zvivakwa kana kuwedzera chinangwa chakanangana.Izvi zvinokonzerwa ne-boronate-based compounds zvakaratidza kuvimbiswa mukurapa kwezvirwere zvakasiyana-siyana, kusanganisira kenza, chirwere cheshuga, uye kuzvimba.Muchidimbu, 3-tert-Butoxycarbonylphenylboronic acid, kana Boc-phenylboronic acid, inowana kushandiswa kwakasiyana-siyana mune organic synthesis uye chemistry yemishonga.Boka rayo reBOC rinoshanda seboka rinodzivirira, richibvumira maitiro ekusarudza pane dzimwe nzvimbo pamorekuru.Uyezve, iyo boronic acid mashandiro anogonesa kabhoni-kabhoni bond maumbirwo, achifambisa kuumbwa kweakaoma organic mamorekuru.Pamusoro pezvo, Boc-phenylboronic acid inoita basa rakakosha mumakemikari ekurapa, uko inoshandiswa mukugadzira boronate-based enzyme inhibitors uye receptor ligands.Pakazere, Boc-phenylboronic asidhi yakakosha reagent inobatsira kufambisira mberi mukugadzira chemistry uye kutsvaga zvinodhaka kuwanikwa.