![3,3′,5,5′-Tetramethyl-[1,1'-biphenyl]-4,4′-diamine Cas:54827-17-7 99% Featured Image](http://cdn.globalso.com/xdbiochems/54827-17-71.jpg)
3,3′,5,5′-Tetramethyl-[1,1'-biphenyl]-4,4′-diamine Cas:54827-17-7 99%
| Catalog Number | XD90518 |
| Product Name | 3,3',5,5'-Tetramethyl-[1,1'-biphenyl]-4,4'-diamine |
| CAS | 54827-17-7 |
| Molecular Formula | C16H20N2 |
| Molecular Weight | 240.34 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29215990 |
Chigadzirwa Specification
| Chitarisiko | Muchena, kubva kuchena kusvika kupfumbu kana yero |
| Assay | >99% |
| Kurasika paKuomesa | <2.0% |
| Zvekutsvaga kushandiswa chete, kwete zvekushandisa kwevanhu | tsvakurudzo inoshandiswa chete, kwete yekushandiswa kwevanhu |
Ricin toxin (RT) ndiyo muchetura wechipiri unonyanya kuuraya unozivikanwa;yakasarudzwa neCDC semumiriri wekusarudza.RT inogadzirwa necastor bhinzi chirimwa;inofungidzirwa kuti 50,000 matani eRT anogadzirwa gore negore sechigadzirwa chemafuta ecastor.RT ine ma subunits maviri, ribotoxic A cheni (RTA) uye galactose-inosunga B cheni (RTB).RT inosungirira kune ese mammalian maseru uye kana yangopinzwa mukati, imwechete RTA inogadzirisa zvese ribosomes muchitokisi.Inotungamirirwa seaerosol, RT inokonzera kukanganisa kwemapapu nekukurumidza uye fibrosis inoteverwa nerufu.Iko hakuna Food and Drug Administration-inotenderwa majekiseni uye marapiro anongoshanda mumaawa mashoma ekutanga mushure mekuratidzwa.Isu takagadzira recombinant RTA yekudzivirira ine maviri ekuchinja V76M/Y80A (RiVax).Iprotein inoratidzwa muEscherichia coli uye haina chepfu uye immunogenic mumakonzo, tsuro, uye vanhu.Kana mbeva dzakabaiwa dzichipikiswa nejekiseni, aerosolized, kana nemuromo (gavaged) RT, dzinodzivirirwa zvachose.Isu takagadzira iyo thermostable, aluminium-adjuvant-ine kugadzirwa kweRiVax uye kuiyedza mu rhesus macaques.Mushure mekubaiwa majekiseni matatu, mhuka dzakagadzira masoja ekudzivirira chirwere aidzidzivirira zvachose kubva pamushonga unouraya weRT.Masoja ekudzivirira chirwere aya akaderedza RT uye aikwikwidzana kusvika pamadhigirii akasiyana-siyana nepaneru yekudzivirira uye isina kutsigira mbeva monoclonal antibodies inozivikanwa kuziva epitopes paRTA yekuzvarwa.Iyo inokonzeresa antibody yemakwikwi mbiri inogona kumiririra immunologic siginecha yekudzivirira.Zvakakosha, siginicha imwe chete yakaonekwa uchishandisa sera kubva kuRiVax-vakabaiwa vanhu.
