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(3S) -3- [4- [(5-Bromo-2-chlorophenyl) methyl]phenoxy]tetrahydrofuran ikemikari yemakemikari inowanikwa mukirasi ye tetrahydrofuran derivatives.Inowanzoshandiswa mumunda wekutsvakurudza kwemishonga uye kubudirira nekuda kwehutano hwayo hunogona kurapa.Chimwe chekushandiswa kukuru kwechikamu ichi chiri mukukwanisa kwayo kuwirirana nemhando dzakasiyana-siyana dzehupenyu, enzymes, kana mapuroteni mumuviri womunhu.Kudyidzana uku kunogona kutungamirira kumodulation yeakananga biochemical nzira, zvingangoguma nemigumisiro yekurapa.Vatsvakurudzi vanowanzoongorora basa rekomboni semumiriri wemishonga yezvirwere zvakasiyana-siyana.Maumbirwo emukomboni, kusanganisira kuvapo kwemhete yetetrahydrofuran uye boka rakatsiviwa rephenyl, zvinobatsira kune zvakasiyana-siyana zvemishonga.Iro phenyl boka rinopa hydrophobic kupindirana, izvo zvinogona kukanganisa kunyungudika kwekomboni uye kusunga hukama kune kunanga mapuroteni.Pamusoro pazvo, kuvapo kwebromine neklorini maatomu mu phenyl ring kunowedzera versatility kukemikari yekomboni reactivity, zvichiita kuti pave nekudyidzana kwakanyanya nemamorekuru akanangana nebiological. -Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran kune zvakagamuchirwa zvinogamuchirwa kana ma enzymes zvinotarisa maitiro ayo ekurapa.Nekuda kweizvozvo, vaongorori vanoongorora mhedzisiro yaro pane akasiyana mamolecular tarisiro, senge mareceptor akabatanidzwa mukuzvimba, kenza, kana central nerve system kusagadzikana.Muzvidzidzo zvepamberi, vaongorori vanogona kuongorora simba rekomboni, kushanda kwayo, uye kuchengetedzwa.Yakasiyana biological assay uye mhando dzemhuka dzinogona kushandiswa kuona maitiro ayo ekuita, kutora, kugovera, metabolism, uye excretion.Iyi data yakakosha pakuongorora pharmacokinetics yekomboni uye kunzwisisa kuti inodyidzana sei nemuviri wemunhu.Zvisinei, zvakakosha kuziva kuti (3S) -3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran. ichiri mudanho rekutsvagisa, uye mashandisirwo ayo angangove ekurapa achiri kuda kuongororwa zvizere.Zvidzidzo zvakakura, kusanganisira miedzo yekiriniki muvanhu, zvingave zvakakosha kuti zvione kuchengetedzwa kwayo uye kushanda kwayo isati yaonekwa sekushandiswa kwekurapa.Pakupedzisira, (3S) -3- [4- [(5-Bromo-2-chlorophenyl)] methyl. ]phenoxy]tetrahydrofuran parizvino iri kuferefetwa pamusoro pezvainogoneka mukurapa mashandisirwo ayo mumunda wekutsvaga kwemishonga.Mamiriro ayo emakemikari akasarudzika anobatsira mukudyidzana kwayo nekwakanangana nebiological tarisiro, kuvhura mikana yekugadzirwa kwenovel kurapa mishonga.Nekudaro, kumwe kutsvagisa uye kuongororwa kunodiwa kuti uone kugona kwayo kwechokwadi semusanganiswa wekurapa.