4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol CAS: 147118-36-3
Catalog Number | XD93412 |
Product Name | 4-(4-Fluorophenyl) -6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol |
CAS | 147118-36-3 |
Molecular Formula | C16H20FN3O3S |
Molecular Weight | 353.41 |
Storage Details | Ambient |
Chigadzirwa Specification
Chitarisiko | Upfu chena |
Assay | 99% min |
4-(4-Fluorophenyl) -6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-yl-methanol, inozivikanwawo seZ6, ikemikari inosanganiswa nemishonga inogona kushandiswa mumunda wemishonga. .Chimiro chayo chakasiyana uye mapoka anoshanda anoita kuti ive inonakidza mumiriri wekutsvaga zvinodhaka nekusimudzira.Imwe inogona kushandiswa yeZ6 ndeye anti-inflammatory agent.Kuzvimba kunoita basa muzvirwere zvakawanda, zvinosanganisira rheumatoid arthritis, kuzvimba bowel chirwere, uye asima.Z6's fluoro-substituted phenyl group uye pyrimidine core inoita kuti ive yakakodzera kuwirirana nezvinangwa zvakananga zvinobatanidzwa muhutano hwehutachiona, zvingave zvichiita kuti pave nekugadzirwa kwezvinonzi anti-inflammatory drugs.Z6 inobatawo chivimbiso se antiviral agent.Utachiona hwehutachiona hunoramba huchinetsa hutano hwepasi rose, uye pane kudiwa nguva dzose kwemishonga mitsva uye inoshanda yeantiviral.Kuvapo kweboka reIsopropyl muZ6 kunowedzera maitiro ayo ehydrophobic, zvichiita kuti ikwanise kupinda mukati mehutachiwana uye inhibit viral replication.Zvimiro zvaro zvekugadzirisa zvinogona kugadziriswa kuti zvinyatsotarisa ma enzymes evhairasi kana mapuroteni, zvichiita kuti pave nekugadzirwa kwemishonga ine simba antiviral.Kuwedzera, Z6 inogona kuva nekushandiswa mukurapa kenza.Iyo fluoro-inotsiva phenyl boka uye pyrimidine core inowanzowanikwa mumisanganiswa ine anticancer chiitiko.Nekugadzirisa iyo Z6 chimiro, zvinogoneka kugadzira zvinobuda zvinonangana nekenza maseru, zvichitadzisa kukura kwavo uye kuitisa apoptosis uku uchichengetedza maseru ane hutano.Iko kunyungudika kwekomboni uye kugadzikana kunogonawo kugadziriswa kuti ivandudze kushanda kwayo uye kuderedza zvingangoitika.Kupfuurirazve, Z6 inogona kushandiswa sechinhu chekutanga chekugadzirwa kwemabhuku maduku emamorekuru kana makemikari scaffolds.Inopa kushanduka kwekugadzirisa nekugadzirisa, zvichibvumira kuongororwa kwehutano-chiito chehukama uye kuzivikanwa kwemishonga inotungamira kuti iwedzere kufambira mberi.Zvimiro zvayo uye mapoka anoshanda anoita kuti ive yakakodzera kune zvakasiyana-siyana zvekurapa zvinangwa, kusanganisira anti-inflammatory, antiviral, uye anticancer applications.Nekumwe kutsvagisa nekusimudzira, Z6 nezvinobvamo zvinobata mukana wekupa mupiro wakakura mukuwanikwa kwezvinodhaka uye kubatsira mukuvandudza kweinoveli uye inoshanda marapirwo.