4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-imwe Cas:951-77-9
| Catalog Number: | XD90580 |
| Cas: | 951-77-9 |
| Molecular Formula: | C9H13N3O4 |
| Molecular Weight: | 227.22 |
| Kuwanikwa | Mudura |
| Mutengo: | |
| Prepack: | 1g USD10 |
| Bulk Pack: | Kumbira Quote |
Chigadzirwa Specification
| Chitarisiko | White crystalline powder |
| Assay | 99% |
| Melting Point | 196°C -200°C |
Thymidine phosphorylase (TP, EC 2.4.2.4) yakaziva chimiro che substrate nehupamhi hwepamusoro, kuburikidza nezvose zviri pasi uye ribosyl moieties.Kutsiviwa kwe3'-OH yethymidine kwakapesvedzera zvakanyanya kuita kwayo kunobatsira neTP.Iko kushandurwa kwepyrimidine nucleosides ine yakagadziridzwa base moieties kune inoenderana 1-phosphate fomu yaive yakashata.Basa reboka rekusiya rakadzikira nekuwedzera kwekunhuhwirira kweiyo pyrimidine base moiety, nekuda kwekuwedzera kuomerwa mukuparadzanisa hwaro nemaamino acids munharaunda kune inoshanda saiti.Kutsiviwa kwe3' uye 5' mapoka anoshanda aiwanzo dzikisa chiyero chekuita uye chikamu chekushandura neTP.Kunyanya iro ribosyl 3' hydroxyl boka raive rakakosha pakusunga kwe substrate ne enzyme.Kinetic assay yakaratidza zvakajeka K(m) uye yakaderera V (max) kukosha pakutsiva iyo 3' hydroxyl boka nehydrogen.
