4-Aminophthalhydrazide AMPPD Cas:3682-14-2 Chiedza chero kusvika kuamber kusvika kuhupfu hwakasvibira kusvika pabundu
| Catalog Number | XD90156 |
| Product Name | 4-Aminophthalhydrazide |
| CAS | 3682-14-2 |
| Molecular Formula | C8H7N3O2 |
| Molecular Weight | 177.16 |
| Storage Details | Chitoro paRT |
Chigadzirwa Specification
| Chitarisiko | Yero yakatsvuka kuita amber kusvika paupfu hwakasvibira kuita bundu |
| Assay | ≥98.0% |
| Density | 1.433 |
| Melting point | 300 ºC |
| Boiling point | 633°C pa760 mmHg |
| Flash point | 336.7°C |
| Solubility | Soluble mu ammonium hydroxide, sodium carbonate kana imwe base. |
1.Takaongorora uye tikaenzanisa mhedzisiro yevashanu H1-antihistamines pane yakakurudzirwa oxidative kuputika pane yakawedzera- uye intracellular level of isolated and stimulated human polymorphonuclear leukocytes.Oxidative kuputika kwemaneutrophils evanhu ari oga akadzidzwa nenzira ye luminol uye isoluminol inowedzerwa chemiluminescence. Kurongeka kwehutano hweH1-antihistamines kuderedza chemiluminescence yakaongororwa extracellularly: dithiaden> loratadine> chlorpheniramine> brompheniramine> pheniramine uye panzvimbo ye-intracellular: loratadine> dithiaden.H1-antihistamines inosiyana zvakanyanya maererano nemakemikari avo oxidative ekuwedzera. - uye intracellular saiti yeyakasarudzika inosimudzira vanhu neutrophils.
2.Chemiluminescence systems yakasimbiswa neisoluminol kana luminol pamwe chete neperoxidase inzira dzakaoma dzekutsvaga reactive oxygen species (ROS) inogadzirwa nephagocyte NADPH oxidase.Iwo maviri ekusimudzira ma substrates akafanana zvakanyanya, anosiyana chete munzvimbo yeboka reamino mumhete inonhuhwirira yemamorekuru.Musiyano uyu unoita kuti isoluminol ive shoma lipophilic molecule iyo isinganyanyi kupinza kune biological membranes.Kushandiswa kweisoluminol nekudaro kunongogumira kuzvidzidzo zvine chekuita nekuvanzika kweokisijeni metabolites.Muchidzidzo ichi tinoratidza kuti synthetic peptides inotorwa kubva kuN-terminal domain ye calcium-regulated protein annexin AI inovhiringidza kuonekwa kwema radicals mune isoluminol-amplified, asi kwete mu luminol-amplified, system.Iyo annexin AI-yakatorwa peptides inoderedza kubuda kwechiedza neisoluminol inonakidzwa ne superoxide uye horseradish peroxidase (HRP) muformyl-methionyl-leucyl-phenylalanine- uye phorbol my ristate acetate-inosimudzira masero, pamwe chete nehydrogen peroxide neHRP.Iyo chaiyo nzira yekudzivisa haizivikanwi.Mhedzisiro yakapihwa inosimbisa kuti kuderedzwa kweserura mhinduro yakaonekwa ine isoluminol-amplified chemiluminescence inofanirwa kusimbiswa neimwe nzira yekuona kuburitswa kwe superoxide anions uye hydrogen peroxide.
