4-Chloro-2-fluoro-3-methoxyphenylboronic acid CAS: 944129-07-1
Catalog Number | XD93459 |
Product Name | 4-Chloro-2-fluoro-3-methoxyphenylboronic acid |
CAS | 944129-07-1 |
Molecular Formula | C7H7BClFO3 |
Molecular Weight | 204.39 |
Storage Details | Ambient |
Chigadzirwa Specification
Chitarisiko | Upfu chena |
Assay | 99% min |
4-Chloro-2-fluoro-3-methoxyphenylboronic asidhi ikemikari ine maapplication akasiyana-siyana muorganic synthesis, chemistry yemishonga, uye zvinhu sainzi.Imwe yekushandiswa kwekutanga kwe4-Chloro-2-fluoro-3-methoxyphenylboronic acid ndeye mukuchinja simbi-catalyzed cross-coupling reactions.Inoshanda se boronic acid kuvaka block, inobvumira kuumbwa kwekabhoni-kabhoni kana kabhoni-heteroatom zvisungo.Semuenzaniso, komisheni iyi inogona kushandiswa muSuzuki-Miyaura cross-coupling reactions, painopindirana nearyl kana vinyl halides pasi pepalladium catalysis kugadzira biaryl makomisheni.Aya maitiro ekubatanidza anoshandiswa zvakanyanya mukugadzirwa kwezvakaoma organic molecules, kusanganisira mishonga yemishonga uye agrochemicals, pamwe nekuvakwa kwezvinhu zvakasikwa.Musanganiswa wakasiyana wechlorine, fluorine, uye methoxy mapoka muchimiro che4-Chloro-2 -fluoro-3-methoxyphenylboronic acid inogonesa kuumbwa kwezvakasiyana-siyana zvinobva kune zvakagadzirirwa zvinhu.Iyo atomu yeklorini inogona kushanda seboka rinotungamira mukuchinja kwesimbi-catalyzed maitiro, ichitungamira maitiro akasarudzika kune chaiwo nzvimbo mukati memorekuru.Fluorine inotsiva inopa yakawedzera lipophilicity, iyo inogona kupesvedzera mukomboni we pharmacokinetic zvimiro uye kuvandudza kwayo bioavailability.Boka remethoxy, kune rumwe rutivi, rinogona kuita seboka rinodzivirira kana kutora chikamu mukuchinja kwakasiyana-siyana kwemakemikari.Mukemikari yemishonga, 4-Chloro-2-fluoro-3-methoxyphenylboronic acid uye zvinyorwa zvayo zvinofadza sevanoda zvinodhaka.Mapoka anoshanda akadai seklorini uye fluorine anogona kuenzanisa kusangana kwekomboni nebiological tarisiro uye kugadzirisa ayo emishonga.Pamusoro pezvo, boka remethoxy rinogona kuwedzera kugadzikana kwemetabolism uye kubatsira kune lipophilicity uye kunyungudika.Zvinhu izvi zvinoita kuti 4-Chloro-2-fluoro-3-methoxyphenylboronic acid ive nzvimbo yakakosha yekutanga kugadzira mishonga mitsva yekurapa muminda yakadai seoncology, zvirwere zvinotapukira, uye kuzvimba. Uyezve, iyo boronic acid moiety mu4-Chloro-2-fluoro. -3-methoxyphenylboronic acid inogona kugonesa kuumbwa kweiyo yakagadzika boronate esters, iyo yakashandiswa mukugadzirwa kwezvinhu zvine hunhu hwakasiyana.Zvinhu izvi zvinogona kuratidza optical, electronic, kana catalytic properties, zvichienderana nekuumbwa kwavo uye chimiro.Kuiswa kwe4-Chloro-2-fluoro-3-methoxyphenylboronic acid kana zvinobva pairi muzvinhu izvi zvinogona kupa mashandiro chaiwo uye kuwedzera mashandiro azvo. nekuda kwemakemikari ayo akasiyana uye kugona kugadzira mamorekuru anoshanda uye zvinhu.Basa rayo mukushandura simbi-catalyzed coupling reactions, yakasanganiswa neyakasiyana midziyo yemapoka ayo anoshanda, inoita kuti ive chishandiso chakakosha muorganic synthesis uye chemistry yemishonga.Pamusoro pezvo, iyo boronic acid moiety inogonesa kuumbwa kweboronate esters, iyo inobatsira mukuvandudzwa kwezvigadzirwa zvepamberi zvine zvimiro zvakagadzirirwa.