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5-(Difluoromethoxy) -2-mercapto-1H-benzimidazole ikemikari inobata zvakakosha mumishonga yakasiyana-siyana.Mushonga uyu ndewekirasi yezvigadzirwa zvebenzimidazole, izvo zvinozivikanwa nekuita kwavo kwemishonga.Imwe yezvinozivikanwa kushandiswa kwe5-(Difluoromethoxy) -2-mercapto-1H-benzimidazole ibasa rayo seanorwisa kenza.Benzimidazole derivatives yakaratidza cytotoxic mhedzisiro inopesana neakasiyana cancer maseru mitsara nekudzivisa kukura kwesero uye kusimudzira apoptosis.Iwo chaiwo mamolecular modifications mu5-(Difluoromethoxy) -2-mercapto-1H-benzimidazole inosimudzira mashandiro ayo ekurwisa gomarara, zvingangovhura magonhi ezvitsva zvingasarudzwa zvekurapa muoncology.Kumwe kushandiswa kwekomboni iyi kuri mumishonga yayo inorwisa utachiona.Benzimidazole derivatives yakaratidza kushanda kweantimicrobial inoshanda kurwisa huwandu hwakawanda hwehutachiona, kusanganisira mabhakitiriya, fungi, uye zvipembenene.Mushonga uyu wakasiyana-siyana wemuumbirwo wezvinhu unobatsira pakukwanisa kwayo kurwisa utachiona, zvichiita kuti ive mumiriri anovimbisa kurwisa utachiona husingaurayiwi nemishonga uye zvirwere zvinotapukira. Uyezve, 5-(Difluoromethoxy) -2-mercapto-1H-benzimidazole yakaratidzira anti-inflammatory activity.Kuzvimba kunoita basa rakakosha mupathogenesis yezvirwere zvakasiyana siyana, kusanganisira zvisingaperi mamiriro senge rheumatoid arthritis uye kuzvimba bowel chirwere.Mushonga wekomboni unopesana nekuputika kunoita kuti ive mukana wekugadzira mishonga mitsva yekurapa kwemamiriro ezvinhu akadaro. Pamusoro pazvo, benzimidazole derivatives yakaongororwawo kuti iite basa rayo mu central nervous system kusagadzikana.Mamwe makomisheni mukirasi ino aratidza neuroprotective mhedzisiro uye kugona kusimudzira ndangariro nekuziva mabasa.Zvinogoneka kuti 5-(Difluoromethoxy) -2-mercapto-1H-benzimidazole inogona kuratidza mhedzisiro yakafanana, zvichiita kuti ive mukana wekuvandudza marapirwo ezvirwere zveurourodegenerative senge hosha yeAlzheimer uye Parkinson.Zvisinei, zvakakosha kuziva kuti 5-(Difluoromethoxy) -2-mercapto-1H-benzimidazole ichiri kuferefetwa, uye kumwe kutsvagurudza kunodiwa kuti uone kugona kwayo kwekurapa kwakazara, kuchengetedzwa, uye mashandisirwo akakwana.Izvo zvakakosha kuti chero angangoita mishonga yemishonga iongororwe zvakasimba, kusanganisira preclinical uye kiriniki miedzo, kuti iratidze kushanda kwayo uye kuchengetedza chimiro. Zvinogara zvakakosha kubvunzana nenyanzvi dzehutano uye nyanzvi mumunda kuti uwane ruzivo rwakakwana uye nhungamiro maererano nemashandisirwo chaiwo. , dosing, uye zvinogona kuitika kune chero mishonga yemishonga.