Products

Biofilms inoumbwa nemasero ebhakitiriya akavharirwa mune yega-yakagadzirwa, extracellular polymeric matrix.Poly-beta (1,6) -N-acetyl-d-glucosamine (PNAG) chinhu chikuru chebiofilm matrix chikamu mu phylogenetically diverse bacteria.Muchidzidzo ichi takaongorora maitiro emuviri uye makemikari ePNAG matrix mune biofilms inogadzirwa mu vitro ne gram-negative porcine rekufema pathogen Actinobacillus pleuropneumoniae uye giremu-positive mudziyo-inobatanidza pathogen Staphylococcus epidermidis.Mhedzisiro yePNAG pakuyerera kwemvura zhinji yakatemwa nekuyera mwero weiyo fluid convection kuburikidza ne biofilms inogadzirwa mu centrifugal sefa zvishandiso.Muyero weconvection yemvura yakakwira zvakanyanya mubiofilms yakasimudzwa pamberi pePNAG-inosvibisa enzyme dispersin B pane biofilms inogadzirwa pasina enzyme, zvichiratidza kuti PNAG inoderedza kuyerera kwemvura zhinji.PNAG yakavharisawo kutakurwa kwequaternary ammonium compound cetylpyridinium chloride (CPC) kuburikidza ne biofilms.Kusungirirwa kweCPC kune biofilms kunowedzera kukanganisa kutenderera kwemvura uye kuvharira kutakurwa kweazo dhayi Allura tsvuku.Bioactive CPC yakanyatsoburitswa kubva kubiofilms nekurapwa ne1 M sodium chloride.Zvakatorwa pamwechete, izvi zvakawanikwa zvinoratidza kuti CPC inobata zvakananga nePNAG matrix uye inoshandura maitiro ayo emuviri nemakemikari.Mhedzisiro yedu inoratidza kuti PNAG inobata basa rakakosha mukudzora mamiriro emuviri webiofilms uye inogona kubatsira kune mamwe maitiro anoenderana nebiofilm akadai sebiocide kuramba.