BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT Cas: 100929-71-3
Catalog Number | XD90431 |
Product Name | BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) MUNYU |
CAS | 100929-71-3 |
Molecular Formula | C21H30N7O17P3.4[C6H13N] |
Molecular Weight | 1142.11748 |
Storage Details | -20 °C |
Chigadzirwa Specification
Chitarisiko | Upfu chena |
Assay | 99% |
NADPH oxidases imhuri yema enzymes anogadzira reactive oxygen marudzi (ROS).Iyo NOX1 (NADPH oxidase 1) uye NOX2 oxidase ndiwo mabviro makuru eROS mumadziro etsinga mumamiriro ezvinhu akadai sehypertension, hypercholesterolaemia, chirwere cheshuga uye kuchembera, uye saka ivo vakakosha vanobatsira mukushushikana kweiyo oxidative, endothelial dysfunction uye vascular kuzvimba kunoenderana. kugadziriswa kwe arterial uye atherogenesis.MuOngororo iyi, tinosimudzira pfungwa iyo inofananidzwa nekushandiswa kweakajairwa antioxidants, inhibiting NOX1 uye NOX2 oxidases inzira yepamusoro yekurwisa oxidative kusagadzikana.Isu tinotsanangura muchidimbu zvimwe zvakajairika uye zviri kubuda zvinoisa NADPH oxidase inhibitors.Pamusoro pezvo, tinosimbisa basa rakakosha reNADPH oxidase regulatory subunit, p47phox, muchiitiko chevascular NOX1 uye NOX2 oxidases, uye tinopa zano kuti kunzwisiswa kuri nani kweiyo chaiyo mamorekuru kupindirana kungagonesa kuvandudzwa kweinoveli isoform-selective zvinodhaka kudzivirira. kana kurapa cardiova scular zvirwere.