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Ceramide imhuri yezvinoitika zvinongoitika lipids inoshanda zvakanyanya muganda repamusoro-soro, ichigadzira chinodzivirira uye ichideredza yakasikwa transepidermal kurasikirwa kwemvura.Ceramide inogadzirisa iyo stratum corneum layer mune ganda rakaoma, kuvandudza hydration yeganda, uye kuwedzera kunzwa kwekupfava.Izvo zvinobatsira kune yakamanikidzwa, inonzwisisika, ine scaly, yakaoma, yakaoma, yakwegura, uye ganda rakakuvadzwa nezuva.Ceramide inoita basa rakakosha muchimiro chepamusoro epidermal layers uye inoumba chikamu chakakosha che intercellular membrane network.Vanobatsira kugadzira uye kuchengetedza ganda rekudzivirira basa.Izvi zvakakosha zvakanyanya: kana iyo stratum corneum's hydration ikachengetwa, saka inoshanda zvakanyanya maererano nekuchinjika uye desquamation, kutendeseka kwayo kunotsigirwa, uye ganda harisi nyore kutsamwa.Kugadzirwa kweceramide kunoderera nezera, kuchisimbisa chero maitiro ekuoma kweganda.Kana yaiswa mugadziriro yekuchengeta ganda, iyo topical application yemaceramides inogona kubatsira iyo stratum corneum kana maceramide akakwanisa kuzadza nzvimbo dzepakati uye kana akaiswa hydrolyzed neiyo chaiyo extracellular enzymes paganda.Kushandisa kwakadai zvakare kunogona kukurudzira kugadzirwa kweceramide muganda, nekudaro ichiwedzera ganda rechisikigo lipid yemukati uye kusimbisa ganda rekudzivirira, rinoyerwa kuburikidza ne transepidermal kurasikirwa kwemvura.Maceramide akaiswa pamusoro akaratidzwa kutora uye kusunga mvura, inodiwa kuti ganda rirambe rakapfava, rakatsetseka, uye rakanyorova.maceramide chaiwo anowanikwa kubva kumhuka nemiti.Nepo maceramide achigona kugadzirwa, zvakawoma kuwana zvakafanana neaya anowanikwa muzvisikwa, achiaita anodhura zvigadzirwa.