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Adsorption yeprotein kune yakasimba-fluid interfaces inowanzowanikwa empirically kusimudzira kuumbwa kweanonyungudika aggregates uye makuru, anooneka, uye anooneka zvidimbu, asi nhanho dzakakosha mukuita uku dzinowanzonetsa kuongorora zvakananga.Aggregation inopindirana neadsorption kumvura-silicon oxide (SiOx) interfaces, yakafanana ne hydrated glass surfaces, yakaonekwa sekushanda kwepH uye ionic simba re alpha-chymotrypsinogen (aCgn) uye ye monoclonal antibody (IgG1).Sero inoyerera inobvumira neutron kuratidza yeprotein layers yakashambadzirwa kuchenesa nzvimbo dzeSiOx, uye mushure mekutevedzana "kusuka" nhanho.Aggregates akadzoreredzwa mumhinduro mushure me "kusuka" zvinyoro nyoro kumusoro kwairatidzwa neutron kuparadzira, microscopy, uye fluorescence spectroscopy.IgG1 mamorekuru anotariswa zvakanyanya "flat" pakatarisana neSiOx pamusoro, iine yekutanga protein layer yakashongedzwa kusvika padiki, nepo inopararira yakavharika yaisukwa zviri nyore.aCgn mamorekuru airamba kunyungudika paaiita kunge avhurwa pachiratidziro, asi neimwe nzira aibviswa zviri nyore.Kune zviitiko apo kusungirirwa kwakasimba kwakaitika, mapuroteni akaita desorb aive musanganiswa wemonomeri uye mashoma eHMW aggregates (ye aCgn) kana subvisible particles (yeIgG1).Shanduko muadsorption uye/kana kuvhurika nepH yakaratidza kuti kupindirana kwemagetsi kwakakosha muzviitiko zvese.