D-Glutamic acid CAS: 6893-26-1 99% White powder
Catalog Number | XD90313 |
Product Name | D-Glutamic acid |
CAS | 6893-26-1 |
Molecular Formula | C5H9NO4 |
Molecular Weight | 147.13 |
Storage Details | Ambient |
Harmonised Tariff Code | 29224200 |
Chigadzirwa Specification
Chitarisiko | White crystalline powder |
Assay | 99% |
Kutenderera chaiko | -31 kusvika -32.2 |
Heavy metals | <10ppm |
AS | <1ppm |
pH | 3 - 3.5 |
SO4 | <0.020% |
Fe | <10ppm |
Kurasika paKuomesa | <0.20% |
Residue paIgnition | <0.10% |
NH4 | <0.02% |
Cl | <0.02% |
State of Solution | >98% |
γ-Glutamyltranspeptidases (γ-GTs) inoparadzanisa γ-glutamyl amide bond ye glutathione uye kuendesa yakasunungurwa γ-glutamyl boka kumvura (hydrolysis) kana kugamuchira amino acids (transpeptidation).Aya ma enzymes anowanikwa munzvimbo dzese anoita basa rakakosha mu biosynthesis uye kuderedzwa kwe glutathione, uye mu xenobiotic detoxification.Pano tinoshuma iyo 3Å resolution yekristaro chimiro cheBacillus licheniformis γ-GT (BlGT) uye iyo yakaoma yayo ine l-Glu.Zvimiro zveX-ray zvinosimbisa kuti BlGT ndeyeN-terminal nucleophilic hydrolase superfamily uye inoratidza kuti puroteni ine nzvimbo yakavhurika inoshanda yakatsemuka yakafanana neyakashumwa kune homologous enzyme kubva kuBacillus subtilis, asi yakasiyana neiyo yakacherechedzwa yemunhu γ-GT uye. ye γ-GTs kubva kune mamwe ma microorganisms.Dhata rinoratidza kuti kusungirirwa kwel-Glu kunokonzeresa kurongeka kweiyo C-terminal muswe weBlGT hombe subunit uye inobvumira kuzivikanwa kwesumbu remasara easidhi ayo anogona kubatanidzwa mukuzivikanwa kwesimbi ion.Basa rezvisaririra izvi pane conformational kugadzikana kweBlGT rakadzidzwa nekuratidzira iyo autoprocessing, enzymatic chiitiko, kemikari uye kupisa kwemafuta mana matsva eAla single mutants.Mhedzisiro yacho inoratidza kuti kutsiva kweAsp568 neAla kunokanganisa zvese autoprocessing uye kugadzikana kweprotein.