Glutathione yakaderedzwa Cas: 70-18-8 98-101% Yakajeka uye isina ruvara
| Catalog Number | XD90284 |
| Product Name | Glutathione yakaderedzwa |
| CAS | 70-18-8 |
| Molecular Formula | C10H17N3O6S |
| Molecular Weight | 307.32 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29309098 |
Chigadzirwa Specification
| Assay | 98% - 101% |
| Chitarisiko | White crystalline powder |
| Giredhi | Ep 7.0 |
| Kusachena A | <0.5% |
| Kusachena B | <0.5% |
| Heavy metals | <10ppm |
| Bacterial endotoxin | <0.10EU/mg |
| Kusachena C | <1.5% |
| Kusachena D | <1.0% |
| Kurasika paKuomesa | <0.5% |
| Solubility | Yakasununguka soluble mumvura, zvishoma soluble mu ethanol uye methylene chloride |
| Iron | <10ppm |
| Chlorides | <200ppm |
| Kuonekwa kweSolution | Zvakajeka uye zvisina ruvara |
| Specific optical rotation | -15.5 kusvika -17.5 |
| Zvose Zvisina Kuchena | <2.5% |
| Ammonium | <200ppm |
| Sulfated ash | <0.1% |
| Sulphates | <300ppm |
| Kusachena E | <0.5% |
Post-translational protein modifications, yakadai setyrosine phosphorylation, inogadzirisa mapuroteni-protein interactions (PPIs) inokosha pakugadzirisa zviratidzo uye cellular phenotypes.Isu takawedzera mbiriso yakasimbiswa mbiri-yakasanganiswa sisitimu inoshandisa vanhu protein kinases yekuongorora yephospho-tyrosine (pY)-inotsamira PPIs mune yakananga kuyedza, yakakura-chiyero maitiro.Takaona 292 kunyanya inoveli pY-inotsamira maPPIs ayo airatidza hunhu hwepamusoro nekuremekedza kinases uye mapuroteni anodyidzana uye akasimbisa chikamu chikuru mu-co-immunoprecipitation miedzo kubva kumasero emammalian.Inenge chikamu chimwe muzvitanhatu chekudyidzana kunoyananiswa neinozivikanwa mutsara wemutsara unosunga motifs nepo ruzhinji rwePY-PPIs rwuchiyananiswa nemamwe mutsara epitopes kana kutongwa neimwe nzira yekuzivikanwa.Kuongororwa kwenetiweki kwakaratidza kuti pY-mediated yekuzivikanwa zviitiko zvakasungirirwa kune yakanyanya kubatana protein module yakatsaurirwa kusaina uye nzira dzekukura kwesero dzine chekuita negomarara.Tichishandisa ma assays anosunga, protein compleme ntation uye phenotypic readouts kuratidza kupindirana kwepY-inotsamira kweTSPAN2 (tetraspanin 2) uye GRB2 kana PIK3R3 (p55γ), isu tinopa muenzaniso wekuti maviri pY-anotsamira PPIs anoraira cellular cancer phenotypes.
