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7-Hydroxygranisetron ikamu rinoshanda semushonga mumunda wemishonga.Iyo ndeyekirasi yemishonga inozivikanwa se selective serotonin 5-HT3 receptor antagonists.Mushonga uyu metabolite yegranisetron, mushonga unowanzo shandiswa antiemetic.Chinangwa chikuru che7-Hydroxygranisetron ndechekudzivirira nekurapa kusvotwa uye kurutsa, kunyanya avo vanobatana nechemotherapy kana nzira dzekuvhiya.Chemotherapy-induced nausea and vomiting (CINV) inonyanya kunetseka kune varwere vekenza vari kurapwa.Izvi zvinogona kukanganisa hupenyu hwemurwere uye zvinogona kukonzera kukanganisa kurapwa.7-Hydroxygranisetron inoshanda nekuvhara chaiyo serotonin receptors mukati mepakati tsinga system, kunyanya iyo iri muchemoreceptor trigger zone uye nzvimbo yekurutsa.Nokuita kudaro, inobatsira kuderedza zviratidzo zvinokonzera kushungurudza uye kurutsa, kupa rubatsiro kune varwere.Pamusoro pekushandiswa kwayo kweCINV, 7-Hydroxygranisetron yakaratidzawo kuvimbiswa mukugadzirisa mushure mekushanda kushungurudza uye kurutsa (PONV).Mushure mekuvhiyiwa, varwere vanowanzosangana nekunzwa kusvotwa uye kurutsa nekuda kwemhedzisiro yeanesthesia nezvimwe zvinhu.7-Hydroxygranisetron inobatsira kudzivirira uye kudzora zviratidzo izvi, zvichiita kuti varwere vadzoke zvakanaka.Kana inoshandiswa, 7-Hydroxygranisetron inowanzopiwa intravenously kana nemuromo, zvichienderana nemamiriro emurwere uye zvinoda kurapwa.Chiyero chinogona kusiyana zvichienderana nehuremu hwemunhu, maitiro kana marapirwo, uye kuoma kwezviratidzo.Zvakakosha kutevera chiyero chakatarwa uye mirayiridzo inopiwa nevashandi vehutano kuti vave nechokwadi chekushanda kwakakwana uye kudzivisa chero zvingangoitika.Kufanana nemishonga yakawanda, 7-Hydroxygranisetron inogona kuva nemigumisiro inogona kuitika.Izvi zvinogona kusanganisira musoro, kuvimbiswa, manyoka, dzungu, uye kuneta.Muzviitiko zvisingawanzoitiki, vanhu vanogona kusangana neallergic reaction kana zvimwe zvakanyanya kuipa.Zvakakosha kuzivisa chero zvine chekuita nezviratidzo kana maitiro kune mupi wehutano kuti aongororwe uye manejimendi akakodzera.Pakupedzisira, 7-Hydroxygranisetron mushonga unoshandiswa zvakanyanya kudzivirira uye kurapa kusvotwa uye kurutsa kunoenderana nekemotherapy uye maitiro ekuvhiya.Nekuvhara mamwe serotonin receptors mukati mepakati tsinga sisitimu, inobatsira kudzikisa izvi zvinoshungurudza zviratidzo muvarwere vegomarara uye vanhu vanopora kubva pakuvhiyiwa.Zvisinei, sezvakaita chero mishonga, iyo