Iodonitrotetrazolium chloride CAS:146-68-9
| Catalog Number | XD90473 |
| Product Name | Iodonitrotetrazolium chloride |
| CAS | 146-68-9 |
| Molecular Formula | C19H13ClIN5O2 |
| Molecular Weight | 505.70 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 32129000 |
Chigadzirwa Specification
| Identification | H-NMR |
| Chitarisiko | Yero yakatsvuka kusvika kuhupfu hweorenji |
| Assay | >99% |
| Solubility | Yakajeka mhinduro |
Interferon-induced transmembrane protein 1 (IFITM1) imwe ye interferon-induced transmembrane mapuroteni emhuri.Muchidzidzo ichi, takashuma kuti iyo yakakwira IFITM1 kutaura mumunhu colorectal cancer (CRC) yakabatana zvakanyanya neCRC lymph node uye kure metastasis pamwe nedanho repamusoro rekiriniki.Zvakanyanya kukosha, yakasimudzwa IFITM1 kutaura chinhu chakazvimirira chekufungidzira kwekusapona.Kuti tiongorore maitiro emakemikari, takaratidza kuti kunyanya-kutaura kweFITM1 muCRC masero akakurudzirwa, asi kugogodza kweFITM1 kutaura kwakarambidzwa, kutama kwemasero / kupinda uye tumorigenicity in vitro.Uyezve, takaona Caveolin-1 (CAV1) sechinangwa chepasi cheFITM1-induced cell invasion, sekugogodza kweCAV1 yakabviswa siIFITM1 yakapindirana inhibition yekupinda kwesero mumasero eCRC.Mukuwedzera, muchikwata cheCRC chevarwere ve229, kutaura kweFITM1 kunopesana nekutaura kweCAV1.Mhedzisiro iyi yakaratidza kuti IFITM1 inosimudzira aggr essiveness yeCRC masero, uye inogona kuita prognostic marker uye kurapa chinangwa cheCRC.
