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Pharmacological mhedzisiro ye theanine

1. Migumisiro panheyo yepakati

Pakuyera mhedzisiro ye theanine pane metabolism ye monoamines munzvimbo dzakasiyana dzehuropi, Heng Yue et al.akawana kuti theanine inogona kukurudzira zvakanyanya kuburitswa kwe dopamine mukati mehuropi hwepakati uye kuvandudza physiological chiitiko che dopamine muuropi.Dopamine ndeyepakati neurotransmitter iyo inomutsa uropi tsinga masero, uye kuita kwayo kwemuviri kunoenderana zvakanyanya nemamiriro emanzwiro emunhu.Kunyange zvazvo maitiro ekuita kwe theanine mukati mehutano hwehutano hwehuropi haisi kunyatsojeka.Asi mhedzisiro ye theanine pamweya uye manzwiro pasina mubvunzo chikamu kubva mumhedzisiro yechiitiko chemuviri chepakati neurotransmitter dopamine.Ehe, iyo anti-kuneta mhedzisiro yekunwa tii inotendwawo kuti inobva pane iyi mhedzisiro kusvika pamwero wakati.

Mune zvimwe zviedzo zvavo, Yokogoshi et al.yakasimbisa kuti kutora theanine kuchakanganisa zvakananga basa repakati neurotransmitter serotonin muuropi zvine chekuita nekudzidza nekuyeuka.

2. Antihypertensive effect

Zvinowanzotendwa kuti kudzora kweBP yemunhu kunokanganisa nekudzivirirwa kwepakati nepakati neurotransmitters catecholamine uye serotonin.Zvidzidzo zvakaratidza kuti theanine inogona kunyatso dzikisa yega hypertension mumakonzo.Kimura et al.aitenda kuti iyo antihypertensive mhedzisiro ye theanine inogona kubva mukudzora kwe secretion yepakati neurotransmitter serotonin muuropi.

Iyo hypotensive effect inoratidzwa ne theanine inogonawo kuonekwa seyakagadzika mhedzisiro kune imwe nhanho.Uye izvi zvinogadzirisa mhedzisiro pasina mubvunzo zvichabatsira kudzoreredza kuneta kwemuviri nepfungwa.

3. Inokanganisa ndangariro

Chu et al.vakashuma kuti vakawana muOperanttest (chiyedzo chekudzidza kwemhuka umo chikafu chinopiwa pamwe nekuchinja kwechiedza) chidzidzo uye vakawana kuti makonzo akapihwa 180 mg ye theanine nemuromo zuva rega rega aive nehunyanzvi hwekudzidza zvichienzaniswa neboka rinodzora.kumwe kuvandudzika.Uye zvakare, mukudzidza kweAvoidance bvunzo (yemhuka yekurangarira kuyedza umo mhuka dzinogashira magetsi mukamuri ine rima padzinopinda mukamuri ine rima nechikafu kubva mukamuri inopenya), inosimbiswa zvakare kuti theanine inogona kuwedzera ndangariro kugona. yemakonzo.Zvidzidzo zvakawanda zvakaratidza kuti mhedzisiro ye theanine mukuvandudza kudzidza uye ndangariro mhedzisiro ye activate yepakati neurotransmitters.

4. Zorora pfungwa dzako nemuviri

Pakare muna 1975, Kimura et al.yakashuma kuti theanine inogona kuderedza iyo yepakati hyperexcitability inokonzerwa necaffeine.Kunyangwe izvo zviri mucaffeine mumashizha etii zviri zvishoma pane zvekofi necocoa, kuvepo kwetheanine kunoita kuti vanhu vafarire kunzwa kunozorodza kana vachinwa tii iyo isina kofi necocoa.

Sezvatinoziva tese, marudzi mana emafungu ehuropi, α, β, σ uye θ, ayo ane hukama zvakanyanya nemamiriro emuviri nepfungwa dzevanhu, anogona kuyerwa pamusoro pehuropi hwedu.Apo Chu et al.vakacherechedza mhedzisiro ye theanine pamafungu ehuropi e15 vakadzi vechidiki vane makore 18 kusvika 22, vakawana kuti iyo α-wave yaive neyakakura yekuwedzera maitiro mushure mekutonga nemuromo kwe theanine kwemaminitsi makumi mana.Asi pasi pemamiriro akafanana ekuedza, havana kuwana mhedzisiro ye theanine pane theta-wave yekutonga kwekurara.Kubva pane izvi mhedzisiro, vanotenda kuti iyo inozorodza yemuviri nepfungwa mhedzisiro inokonzerwa nekutora theanine haisi yekuita kuti vanhu varare, asi kugadzirisa pfungwa.

5. Zvokudya zvine utano

Zvizhinji zvezvigadzirwa zvehutano zvekudya pamusika ndezvekudzivirira kana kuvandudzwa kwezvirwere zvevakuru.Chikafu chehutano senge theanine isiri yehypnotic, asi zvakare inobvisa kuneta, inoderedza BP uye inovandudza kudzidza uye kugona kuyeuka hazviwanzo uye zvinobata maziso.Nechikonzero ichi, theanine akahwina mubairo wedhipatimendi rekutsvagisa kuInternational Food Raw Materials Musangano wakaitirwa kuGermany muna 1998.

Theanine ndiyo amino acid ine yakakwira zvirimo mutii, inodarika 50% yehuwandu hwemahara amino acids uye 1% -2% yehuremu hwakaoma hwemashizha etii.Theanine ichena-yakaita sono muviri, inonyungudika nyore mumvura.Iine tambo inotapira uye inozorodza uye inhengo yekuravira kwetii.MaJapan anowanzo shandisa shading kuwedzera zvirimo zve theanine mumashizha etii kuwedzera kutsva kwemashizha etii.

(1) Kutora uye metabolism.

Mushure mekutonga nemuromo kwe theanine mumuviri wemunhu, inotorwa nemudumbu bhurashi muganhu mucosa, inopinda muropa, uye inoparadzirwa kune matishu uye nhengo kuburikidza nekutenderera kweropa, uye chikamu chinoburitswa muweti mushure mekuora ne itsvo.Kuwanda kwe theanine yakanyudzwa muropa nechiropa kwakadzikira mushure meawa imwe, uye theanine muuropi yakasvika pakakwirira mushure memaawa mashanu.Mushure memaawa makumi maviri nemana, theanine mumuviri wemunhu yakanyangarika uye yakaburitswa seweti.

(2) Rongedza shanduko yemaurotransmitters muuropi.

Theanine inokanganisa metabolism uye kusunungurwa kwemaurotransmitters akadai se dopamine muuropi, uye zvirwere zvehuropi zvinodzorwa nemaurotransmitters aya zvinogonawo kudzorwa kana kudzivirirwa.

(3) Kuvandudza mano okudzidza uye ndangariro.

Mukuedza kwemhuka, zvakaonekwawo kuti kugona kudzidza uye ndangariro yemakonzo anotora theanine aive nani pane ayo eboka rinodzora.Mukuedza kwemhuka, zvakaonekwa kuti kugona kudzidza kwakaedzwa mushure mekutora theanine kwemwedzi 3-4.Mhedzisiro yebvunzo yakaratidza kuti iyo dopamine yekusangana kwemakonzo anotora theanine yaive yakakwira.Kune marudzi akawanda ebvunzo dzekugona kudzidza.Imwe ndeyekuisa mbeva mubhokisi.Pane chiedza mubhokisi.Kana mwenje wabatidzwa, dzvanya switch uye chikafu chinobuda.Mbeva dzinotora theanine dzinogona kugona zvakakosha munguva pfupi, uye kugona kudzidza kwakakwira kupfuura kwembeva dzisingatore theanine.Chechipiri kutora mukana wetsika yembeva yekuhwanda murima.Mbeva painomhanya murima, inorohwa nehana nemagetsi.Mbeva dzinotora theanine dzinowanzomira munzvimbo inopenya kudzivirira kuvhunduka kwemagetsi, zvichiratidza kuti zvine njodzi kunzvimbo ine rima.ndangariro yakasimba.Zvinogona kuonekwa kuti theanine ine mhedzisiro yekuvandudza ndangariro uye kugona kudzidza kwemakonzo.

(4) sedative effect.

Caffeine chinhu chinozivikanwa chinokurudzira, asi vanhu vanonzwa vakasununguka, vakadzikama, uye mune hunhu hwakanaka pavanonwa tii.Izvo zvakasimbiswa kuti izvi zvinonyanya kuitika kwe theanine.Kudya panguva imwe chete yecaffeine uye amino acids kune yakakosha inhibitory mhedzisiro pakunakidzwa.

(5) Kuvandudza chirwere chekuenda kumwedzi.

Vakadzi vazhinji vane chirwere chekutevera.Menstrual syndrome chiratidzo chekusagadzikana kwepfungwa uye mumuviri muvakadzi vane makore 25-45 mumazuva 3-10 vasati vaenda kumwedzi.Mupfungwa, zvinonyanya kuratidzwa sekuva nyore kutsamwa, kutsamwa, kuora mwoyo, kusagadzikana, kusakwanisa kuisa pfungwa, etc. Pamuviri, zvinonyanya kuratidzwa sekuneta nyore, kuoma kurara, musoro, kurwadziwa kwechipfuva, kurwadziwa kwepazasi kwedumbu, musana, maoko anotonhora uye tsoka, etc. The sedative effect ye theanine inouyisa kurangarira mashandiro ayo anozorodza pakuenda kumwedzi syndrome, iyo yakaratidzwa mumakiriniki ekuedzwa kuvakadzi.

(6) Chengetedza masero etsinga.

Theanine inogona kutadzisa nerve cell kufa kunokonzerwa nechinguvana cerebral ischemia, uye ine inodzivirira pamasero etsinga.Kufa kwemasero etsinga kwakabatana zvakanyanya neiyo excitatory neurotransmitter glutamate.Kufa kwesero kunoitika pamberi pe glutamate yakawandisa, iyo inowanzova chikonzero chemamiriro ezvinhu akadai seAlzheimer's.Theanine yakarongeka yakafanana ne glutamic acid uye inokwikwidza kune inosunga nzvimbo, nekudaro ichivharira nerve cell kufa.Theanine inogona kushandiswa pakurapa nekudzivirira kukanganiswa kwehuropi kunokonzerwa ne glutamate, senge cerebral embolism, cerebral hemorrhage uye mamwe cerebral apoplexy, pamwe nezvirwere zvakadai sekushaikwa kweropa uye senile dementia inoitika panguva yekuvhiyiwa kwehuropi kana kukuvara kwehuropi.

(7) Mhedzisiro yekuderedza BP.

Mukuedza kwemhuka, injecting theanine mu hypertensive spontaneous rats, diastolic blood pressure, systolic blood pressure uye avhareji yeropa yakaderedzwa, uye dhigirii yekuderedza yakanga yakabatana nedhesi, asi pakanga pasina kuchinja kukuru kwemwoyo;theanine yaibudirira mumakonzo eropa.Pakanga pasina kudzikisa kweropa, zvichiratidza kuti theanine yaingove nekudzikisa kweropa pamakonzo ane hypertensive.Theanine inogona kuderedza BP nekugadzirisa kuungana kwemaurotransmitters muuropi.

(8) Wedzera kushanda kwemishonga inorwisa gomarara.

Kurwara negomarara uye kufa kuri kuramba kwakakwira, uye mishonga inogadzirwa kurapa kenza inowanzova nemigumisiro yakasimba.Mukurapa kenza, kunze kwekushandiswa kwemishonga inorwisa cancer, mishonga yakasiyana-siyana inodzvinyirira mhedzisiro yavo inofanira kushandiswa panguva imwe chete.Theanine pachayo haina anti-bundu basa, asi inogona kuvandudza basa reakasiyana anti-bundu zvinodhaka.Kana theanine nemishonga inorwisa bundu ikashandiswa pamwe chete, theanine inogona kudzivirira mishonga inorwisa bundu kubva mukuyerera kubva mumasero ebundu uye kuwedzera simba rekurwisa gomarara remishonga inorwisa bundu.Theanine inogonawo kuderedza migumisiro yeantineoplastic zvinodhaka, zvakadai sekugadzirisa chiyero che lipid peroxidation, kuderedza migumisiro yakadai sekuderedzwa kwemasero machena eropa uye masero emapfupa emapfupa anokonzerwa nemishonga inonzi antineoplastic.Theanine zvakare ine mhedzisiro yekudzivisa kupinda kwekenza maseru, inova nzira inodiwa kuti masero egomarara apararire.Kudzivisa kupinda kwayo kunomisa gomarara kupararira.

(9) Kurasikirwa kwehuremu

Sezvatinoziva tese, kunwa tii kune mhedzisiro yekurasikirwa uremu.Kunwa tea kwenguva yakareba kunoita kuti vanhu vaonde uye kubvisa mafuta evanhu.Kurasikirwa kwehuremu hwetii mhedzisiro yekubatana kwekuita kweakasiyana zvikamu mutii, kusanganisira theanine, iyo inoshanda chaizvo mukuderedza cholesterol mumuviri.Pamusoro pezvo, theanine yakawanikwa zvakare ine kuchengetedzwa kwechiropa uye antioxidant mhedzisiro.Kuchengetedzeka kwe theanine kwakaratidzawo.

(10) Anti-kuneta mhedzisiro

Zvidzidzo zvakawana kuti theanine ine anti-kuneta mhedzisiro.Kutungamirirwa nemuromo kwemishonga yakasiyana-siyana ye theanine kune mbeva kwemazuva makumi matatu inogona kurebesa kureba-inotakura nguva yekushambira yemakonzo, kuderedza kushandiswa kwechiropa glycogen, uye kuderedza chiyero che serum urea nitrogen inokonzerwa nekurovedza muviri;ine simba rakakosha pakuwedzera kweropa lactate mumakonzo mushure mekurovedza muviri.Inogona kukurudzira kubviswa kweropa lactate mushure mekurovedza muviri.Naizvozvo, theanine ine anti-kuneta mhedzisiro.Iyo nzira inogona kunge yakabatana neiyo theanine inogona kuvharira secretion ye serotonin uye kukurudzira secretion ye catecholamine (5-hydroxytryptamine ine inhibitory mhedzisiro pane yepakati tsinga system, nepo catecholamine ine excitatory effect).

(11) Kuvandudza kudzivirirwa kwevanhu

Kuedza kuchangobva kupedzwa neHarvard University kuUnited States kwakaratidza kuti green tea, oolong tii uye zvigadzirwa zvetii zvine huwandu hwakawanda hwemapoka emamino, izvo zvinogona kuvandudza kugona kwekushanda kwemasero ekudzivirira emunhu uye kuwedzera kugona kwemuviri wemunhu kurwisa zvirwere zvinotapukira.

Kushandiswa kwe theanine mumunda wekudya

Kubva muna 1985, iyo US Food and Drug Administration yakaziva theanine uye yakasimbisa kuti iyo synthetic theanine inowanzo zivikanwa sechinhu chakachengeteka (GRAS), uye hapana chinorambidzwa pahuwandu hwekushandiswa panguva yekushandiswa.

(1) Zvinoshanda zvekuwedzera zvekudya: Theanine ine mabasa ekusimudzira kusimba kwemafungu ealpha muuropi, achiita kuti vanhu vanzwe vakasununguka uye vachivandudza ndangariro, uye vakapfuura miedzo yevanhu.Naizvozvo, inogona kuwedzerwa kune chikafu sechinhu chinoshanda chekugadzira chikafu chinoshanda chinobvisa kushushikana kwekutya uye kuvandudza njere.Zvidzidzo zvakasimbisawo kuti theanine inogona kuwedzerwa kune zvihwitsi, zvinwiwa zvakasiyana, nezvimwe kuti uwane yakanaka sedative mhedzisiro.Parizvino Japan iri kuita basa rekutsvagisa nekusimudzira munzvimbo iyi.

(2) Kuvandudza kunaka kwezvinwiwa zvetii

Theanine ndicho chikamu chikuru chekunaka uye kunozorodza kwetii, iyo inogona kuvhara kuvava kwecaffeine uye kuvava kwetii polyphenols.Parizvino, nekuda kwekudzikiswa kwezvigadzirwa uye tekinoroji yekugadzira, kutsva uye kunozorodza kuravira kwezvinwiwa zvetii munyika yangu kwakashata.Naizvozvo, muzvinwiwa zveti Kuwedzera imwe huwandu hwe theanine panguva yekukura kunogona kuvandudza zvakanyanya kunaka uye kunaka kwezvinwiwa zveti.Chinwiwa che "tii mbishi" chichangobva kugadzirwa neJapan Kirin Company chinowedzerwa ne theanine, uye kubudirira kwayo kukuru mumusika wechinwiwa weJapan muenzaniso chaiwo.

(3) Flavour kunatsiridza maitiro

Theanine haigone kushandiswa chete sechinhu chinonakisa chegirini tii, asi zvakare inogona kuvharidzira kuvava uye astringency mune zvimwe zvekudya, kuitira kuti inatsiridza kunaka kwechikafu.Cocoa zvinwiwa uye tii yebhari zvine kuravira kwakasiyana-siyana kana kunhuhwirira, uye iyo yakawedzerwa sweetener ine kuravira kusingafadzi.Kana 0.01% theanine ikashandiswa kutsiva sweetener, mibairo inoratidza kuti kunaka kwechinwiwa chakawedzerwa ne theanine kunogona kuvandudzwa zvakanyanya.kuitira kuvandudzwa.

(3) Zvikumbiro mune mamwe mabasa

Theanine inogona kushandiswa semvura inonatsa kuchenesa mvura yekunwa;kushandiswa kwe theanine sechinhu chinoshanda mu deodorant kwave kushumwa mumapatent echiJapan.Imwe patent inoshuma kuti chinhu chine theanine chikamu chinogona kutadzisa kutsamira mupfungwa.Theanine inoshandiswa semoisturizer muzvizoro uye sechikafu chinonyorovesa ganda.