Chiedza chegirini SF Cas: 5141-20-8 Yakadzika yepepuru poda
| Catalog Number | XD90538 |
| Product Name | Chiedza chegirini SF |
| CAS | 5141-20-8 |
| Molecular Formula | C₃₇H₃₄N₂Na₂O₉S₃ |
| Molecular Weight | 792.86 |
| Storage Details | -15 kusvika -20 °C |
| Harmonised Tariff Code | 32129000 |
Chigadzirwa Specification
| Chitarisiko | Upfu hwepepuru hwakadzama |
| Assay | 99% |
| Solubility | Soluble mumvura kupa yakajeka green solution |
Kuongorora zvakarongeka maitiro ekusvibisa uye kuchengetedzeka kwedhayi nyowani dzinogona kuvhiyiwa intraocular. Dhayi nhanhatu dzakaiswa mukuferefeta: yakasvibira yakasvibirira SF (LGSF) yero, E68, bromophenol yebhuruu (BPB), Chicago yebhuruu (CB), rhodamine 6G, rhodulinblau. -basic 3 (RDB-B3).Dhayi dzose dzakanyungudutswa uye dzakanyungudutswa mune yakaenzanirana saline saline solution.Chiedza chinobvisa chiedza chedhayi imwe neimwe chakayerwa pahuwandu hwe0.05% pakati pe200 ne1000 nm.Mamiriro ekusvibisa akaongororwa nekusvibisa lens capsule tissue uye epiretinal membranes (ERMs), yakabviswa intraoperative, ine dhayi ye1.0%, 0.5%, 0.2%, uye 0.05%.Enucleated porcine maziso (postmortem nguva, maawa 9) akasvibiswawo.Dye-inoenderana chepfu yakaongororwa ne colorimetric test (MTT) kuyera inhibition ye retinal pigment epithelium (RPE) cell proliferation (ARPE-19 uye primary human RPE masero, ndima 3-6).Kushanda kwesero kwakaverengerwawo zvichienderana neaviri-mavara fluorescence cell-viability assay.Dhayi dzakaongororwa muzvikamu zve 0.2% uye 0.02%.Madhayi ose akaongororwa muchidzidzo ichi akasvibisa ma lens capsules evanhu, akabviswa intraoperative;ERMs, yakasvunurwa panguva yekuvhiya macular pucker;uye enucleated porcine maziso, zvichienderana nekutarisa kwakaiswa.Iyo yakareba-wavelength yekunyura yakawanda yedhayi yaive mukati meiyo 527 kusvika 655 nm pamisumbu ye0.05%.Rhodamine G6 uye RDB-B3 yakaratidza migumisiro yakaipa paARPE-19 kuwedzera kwesero pamusangano we 0.2% uye yakabviswa kubva pakutsvakurudza mberi mumaseru ekutanga eRPE.Iwo mana akasara madhayi haana kuratidzira muchetura paARPE-19 uye yekutanga RPE cell kuwanda pazvikamu zve0.2% uye 0.02%.Kushanda kwesero kwakakanganiswa neLGSF yero (0.2%) uye CB (0.2% uye 0.02%).Madhayi maviri (E68 uye BPB) haana kuratidza huturu hwakakodzera mu vitro.Kuongororwa kwakarongeka kwemadhayi ekushandiswa kwemukati mekuona kunoita sekusungirwa.Muchidzidzo ichi madhayi mana akaonekwa aine hunhu hunoshanda, aine maviri emadhayi aya asina chinooneka chepfu pamasero eRPE mu vitro.
