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Nzira dzekurapa T2DM, chirwere chinoratidzwa nehuviri chirema cheislet cell dysfunction uye insulin kuramba, zvinosanganisira vamiririri vanowedzera secretion ye insulin nepancreas (secretagogues), vamiririri vanowedzera kunzwisiswa kwenhengo dzinotangwa kune insulin (sensitizers), uye Liraglutide, GLP-1 receptor agonist kuti isvike kumusika, ine 97% homology kuGLP-1 ine maviri chete amino acid shanduko uye nekuwedzera kweiyo fatty acid parutivi cheni.Kunyanya, iyo lysine iri pachinzvimbo 34 yakatsiviwa nearginine, uye lysine iri pachinzvimbo 26 yakagadziridzwa neC16 acyl chain kuburikidza ne glutamoyl spacer.Liraglutide inowana kuramba kwayo kuDPP-4 kudzikira kubva pakusimba kwayo kugadzira micelles uye kusunga kune albumin.Kusiyana neyakatangira exenatide, iyo inoda majekiseni maviri ezuva nezuva epasi pekutanga uye ekupedzisira kudya kwezuva, liraglutide inotenderwa seyakamwe-zuva nezuva kurapwa regimen uye inogona kushandiswa pamwe chete nemetformin kana sulfonylurea kune varwere vasina kukwana glycemic control ine chero. monotherapy kana kusanganiswa kwemaviri kurapwa.Iyo zvakare inotenderwa pamwe chete neaviri kurapa kwemetformin uye thiazolidinedione mune varwere vasina kukwana glycemic control.Liraglutide yakaratidza inosunga potency ye61 pM (EC50 = 55 pM yeGLP-1) kune yakaumbwa munhu GLP-1 receptor.