Losartan CAS: 114798-26-4
Catalog Number | XD93387 |
Product Name | Losartan |
CAS | 114798-26-4 |
Molecular Formula | C22H23ClN6O |
Molecular Weight | 422.91 |
Storage Details | Ambient |
Chigadzirwa Specification
Chitarisiko | Upfu chena |
Assay | 99% min |
Losartan mushonga uri wekirasi yemishonga inozivikanwa seangiotensin II receptor blockers (ARBs).Inonyanya kushandiswa kurapa high blood pressure (hypertension) uye mamwe marudzi emwoyo mamiriro ezvinhu.Hypertension inowanzoonekwa nepamusoro-soro yeropa.Kana ikasarapwa, inogona kutungamirira kumatambudziko akakomba ehutano akadai sehosha yemwoyo, sitiroko, uye matambudziko eitsvo.Losartan inoshanda nekuvharira kuita kwehomoni inonzi angiotensin II, iyo inomisa tsinga dzeropa uye inoita kuti BP ikwire.Nekudzivisa iyi hormone, losartan inobatsira kusunungura uye kuwedzera mitsipa yeropa, nokudaro kuderedza ropa.Kuwedzera pakurapa hypertension, losartan inobatsirawo kune mamwe mamiriro emwoyo, akadai sekushaya mwoyo uye kuruboshwe ventricular hypertrophy.Inogona kubatsira kuvandudza zviratidzo, kuwedzera kushanda kwemwoyo, uye kuderedza dambudziko rezviitiko zvemwoyo kune varwere vane mamiriro ezvinhu aya.Kupfuurirazve, losartan yakawanikwa ine simba rekudzivirira itsvo kune vanhu vane chirwere cheshuga 2 uye chirwere cheshuga nephropathy (chirwere chetsvo).Inogona kuderedza kufambira mberi kwekukuvara kwetsvo, kuderedza proteinuria (protein yakawandisa muweti), uye kubatsira kuchengetedza kushanda kwetsvo muvanhu ava.Dosing uye kushandiswa kwe losartan kunogona kusiyana zvichienderana nemamiriro emunhu, makore, nezvimwe zvinhu.Inowanzo kutorwa nemuromo kamwe pazuva, kana pasina chikafu.Zvakakosha kutevedzera chipimo chemushonga uye mirairo yakapihwa nenyanzvi yezvehutano.Semushonga chero upi zvawo, losartan inogona kuve nemhedzisiro inokonzeresa.Zvinowanzoitika zvinogona kusanganisira dzungu, kuneta, kutemwa nemusoro, uye kugumbuka mudumbu.Zvinokurudzirwa kuzivisa chero mhedzisiro yakaoma kana inoenderera kune mupi wehutano.Muchidimbu, losartan is angiotensin II receptor blocker inowanzoshandiswa pakurapa hypertension, mamiriro emoyo senge kutadza kwemoyo, uye diabetic nephropathy.Nekuvhara chiito cheangiotensin II, losartan inobatsira kuzorora uye kuwedzera tsinga dzeropa, nekudaro kuderedza kukwira kweropa nekuvandudza kushanda kwemoyo.Mushonga unokosha mukugadzirisa aya mamiriro uye unofanirwa kutorwa sekurairwa nenyanzvi yezvehutano.