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Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)CAS: 289042-11-1
| Catalog Number | XD93411 |
| Product Name | Methyl 4-(4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6) |
| CAS | 289042-11-1 |
| Molecular Formula | C17H20FN3O4S |
| Molecular Weight | 381.42 |
| Storage Details | Ambient |
Chigadzirwa Specification
| Chitarisiko | Upfu chena |
| Assay | 99% min |
Methyl 4-(4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate, inozivikanwawo seZ6, isanganiswa ine zvakasiyana-siyana zvinogona kushandiswa mumunda wemishonga. .Kuvapo kweboka refluoro-inotsiva phenyl rakasungirirwa papyrimidine ring rinoratidza kuti Z6 inogona kupindirana nezvinangwa zvehupenyu, zvichiita kuti ive mumiriri anovimbisa kuedza kutsvaga zvinodhaka.Kubatanidzwa kweboka reIsopropyl kunowedzera hydrophobicity yekomboni, inogona kuvandudza kukwanisa kwayo kupinda mukati me membrane yehupenyu uye kusvika kune chinangwa chekutsvaga.Iri boka rinoshanda rave richibatanidzwa nekusimudzira kugadzikana kwemetabolism yekomboni uye kuderedza zvingangoitika kunze kwechinangwa.Inogonawo kubatsira mukunyungudika kwekomboni munzvimbo dzepolar.Zvinhu izvi zvinogona kuva zvakakosha mukugadzirwa kwebioactive compounds.Kuvapo kweboka remethyl ester muZ6 rinopa chiyero chekugadzikana uye nyore kubata.Uyezve, boka re carboxylate pa 5-nzvimbo ye pyrimidine ring inogona kushanda senzvimbo inogona kushandiswa kwemakemikari kugadziriswa, zvichibvumira zvidzidzo zvehukama-maitiro ehukama uye optimization yemishonga yemishonga.Z6's structural features inoratidza kuti inogona kunge iine simba rekushandisa semishonga inoshanda. ingredient (API) yekurapa zvirwere zvakasiyana-siyana.Inogona kuongororwa nekuda kwekugona kwayo seanorwisa-kuzvimba mumiriri, antiviral mushonga, kana mukurapa cancer.Musanganiswa wakasiyana-siyana wemapoka anoshanda anogona kupa mikana yekusarudza kudyidzana kwebhayoloji, zvichiita kuti ive mukwikwidzi anoyevedza wekugadzirisa zvinodhaka. Uyezve, kuomarara kweZ6 uye kusiyana kwakasiyana kunoita kuti ive nzvimbo inonakidza yekutangisa kugadzirwa kwemaraibhurari madiki mamorekuru kana scaffolds makemikari.Inogona kushanda sechivakwa chekugadzirisa kwezvakagadzirwa zvakasiyana-siyana zvinotorwa, zvichigonesa kuongororwa kwehukama-chiitwa hukama uye kuzivikanwa kweanotungamira makomisheni kuti awedzere optimization.Pakupedzisira, Z6, ine akasiyana maumbirwo ayo uye mapoka anoshanda, ine vimbiso zvakasiyana-siyana zvemishonga.Kugona kwayo se API, yakasanganiswa nekusiyana-siyana kuti igadziriswe uye kugadziridzwa, inoita kuti ive musanganiswa unonakidza wekutsvaga zvinodhaka uye kuedza kwekusimudzira.Zvimwe zvidzidzo uye kutsvagisa zvinodiwa kuti uongorore zvizere uye ushandise kugona kwayo kwekurapa.
