Penicillin G potassium munyu CAS: 113-98-4 99% Poda yakachena
| Catalog Number | XD90351 |
| Product Name | Penicillin G potassium munyu |
| CAS | 113-98-4 |
| Molecular Formula | C16H17KN2O4S |
| Molecular Weight | 372.48 |
| Storage Details | Ambient |
| Harmonised Tariff Code | 29411000 |
Chigadzirwa Specification
| Kurasika paKuomesa | <1.0% |
| Rudzi rweKugadzirisa | Haina kunyanyisa kupenya kupfuura kusimba Y2 kana YG2 yemhando yereferensi |
| pH | 5-7.5 |
| Related Substances | <1.0% |
| Assay | 99% |
| Potency | 1440 - 1680u/mg |
| Chitarisiko | Ichena kusvika kuchena yekristaro hupfu |
| Kujeka Kwemhinduro | Kwete kupfuura opalescent kupfuura referensi kumiswa 1 |
| Transmittance | NLT 90% |
| Butyl acetate | NMT 0.05% |
| Butanol | NMT 0.12% |
e yakatsanangura kare kuti autoinducer molecule, inozivikanwa se1,3-diaminopropane (1,3-DAP), yakavanzwa nePenicillium chrysogenum uye Acremonium chrysogenum.Tichishandisa pH-inodzorwa fermentor tsika takaona mubasa iri kuti 1,3-DAP uye spermidine zvinonyatso kurudzira biosynthesis ye benzylpenicillin muP. chrysogenum, zvose zvakatsanangurwa uye mumagetsi ekugadzira penicillin.Zvose 1,3-DAP uye spermidine, asi kwete putrescine (1,4-diaminobutane), inobereka kuwedzera kwakanyanya muzvinyorwa zvinyorwa zvepenicillin biosynthetic gene pcbAB, pcbC uye penDE.Aya ma polyamines haakonzeri kutaura kwepasi rose pH-stress regulator pacC gene, saka zvisingabatanidzi kuti mhedzisiro ye1,3-DAP uye spermidine inokonzerwa nekushandurwa kweiyo pH control mechanism.Kutaridza kwemajini matatu epenicillin biosynthetic kwakaderedzwa zvakanyanya mulaeA-knock-down mutant yeP. chrysogenum, inoburitsa mwero wakaderera zvikuru webenzylpenicillin.Sezvineiwo, 1,3-DAP uye spermidine inodzoreredza mhedzisiro yelaeA kugogodza-pasi shanduko, kudzoreredza zvizere mwero wekugadzirwa kwepenicillin.Uyezve, 1,3-DAP uye spermidine zvakasimudzira kutaura kweLaeA mumatambudziko evabereki uye yakadzoreredza mazinga eAA zvinyorwa mulaeA knock-down mutant.Kutorwa pamwe chete mhedzisiro iyi inoratidza kuti kusimudzira mhedzisiro yeinducer mamorekuru 1,3-DAP uye spermidine inoitwa, kanenge muchikamu, kuburikidza nekukurudzira kwekutaura kwelaeA, mutongi wepasi rose anoita epigenetically pakutaura kwechipiri metabolite majini. ne heterochromatin reorganization.
