PVP-K30 Cas: 9003-39-8 Ichena kusvika kune yero chena poda
Catalog Number | XD90232 |
Product Name | PVP-K30 |
CAS | 9003-39-8 |
Molecular Formula | C8H15NO |
Molecular Weight | 141.2108 |
Storage Details | Ambient |
Harmonised Tariff Code | 39059990 |
Chigadzirwa Specification
Mvura | <5% |
Heavy metals | <10ppm |
pH | 3 - 7 |
Residue paIgnition | <0.1% |
Aldehydes | 0.05% yakawanda |
Nitrogen | 11.5 - 12.8% |
Chitarisiko | Hupfu huchena kusvika kune yero |
K Kukosha | 27 - 32.4 |
Hydrazine | 1.0% max |
Assay | 99% |
Takaongorora kugadzikana kwemuviri kweamorphous curcumin dispersions uye basa recurcumin-polymer intermolecular kupindirana mukunonoka crystallization.Curcumin inonakidza modhi musanganiswa sezvo ichigadzira zvese intra uye intermolecular hydrogen zvisungo mukristaro.Iyo yakarongeka yakasiyana-siyana yeamorphous dispersion polymers yakaongororwa;poly(vinylpyrrolidone), Eudragit E100, carboxymethyl cellulose acetate butyrate, hydroxypropyl methyl cellulose (HPMC) uye HPMC-acetate succinate.Mid-infrared spectroscopy yakashandiswa kuona uye kuyera huwandu hwekubatana kwe curcumin-polymer.Kugadzikana kwemuviri pasi pemamiriro akasiyana ezvakatipoteredza akatariswa nehupfu X-ray diffraction.Curcumin kugadzikana kwemakemikari kwakatariswa neUV-Vis spectroscopy.Kuparadzaniswa kweamorphous curcumin yakagadzikana kwakanga kwakaoma mukusavapo kwemapolymers.Mapolymers akaratidza kuti anoshanda curcumin crystallization inhibitors anogonesa kugadzirwa kweamorphous solid dispersions;zvisinei, mapolymers airatidza kugona kwakasiyana kwazvo kurambidza crystallization panguva yekuchengetedza kwenguva refu.Curcumin intramolecular hydrogen bonding yakaderedza kuwanda kweiyo hydrogen bonding nemapolymers;saka mapolymers mazhinji akange asina kunyatsoshanda crystallization inhibitors.Pakazara, mapolymers airatidza kuve crystallization inhibitors, asi inhibition yaive shoma nekuda kweiyo intramolecular hydrogen bonding mu curcumin, izvo zvinotungamira mukudzikira kwekugona kwemapolymer kudyidzana pamwero wemolecular.