Spectinomycin dihydrochloride pentahydrate CAS: 22189-32-8 White crystaline poda
Catalog Number | XD90369 |
Product Name | Spectinomycin dihydrochloride pentahydrate |
CAS | 22189-32-8 |
Molecular Formula | C14H24N2O7·2HCl·5H2O |
Molecular Weight | 495.30 |
Storage Details | 2 kusvika ku8 °C |
Harmonised Tariff Code | 29419090 |
Chigadzirwa Specification
Assay | 99% |
Chitarisiko | White crystaline powder |
Kuongorora mamolecular epidemiology yezvitsaura zveNeisseria gonorrhoeae kubva kuSaskatchewan, Canada, uchishandisa Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), uye kuongorora masangano pakati peantimicrobial susceptibility (AMS) uye mamwe marudzi emhando (STs). , yakaunganidzwa pakati pe2003 ne2008, yakanyorwa neNG-MAST.STs dzakaiswa mumapoka kana imwe yealleles yavo yakanga yakajairika uye imwe yakasiyana ne ≤1% mukutevedzana kweDNA.AMS yakatemwa neagar dilution (CLSI) kune manomwe maantibiotics.N gonorrhoeae isolates yakagadziriswa kuita 82 yega NG-MAST STs uye 18 NG-MAST ST mapoka ane mapoka 25, 3655, 921, 3654, 3657 uye 3656 anosanganisira 53.4% (18. /320) yezvitsaurwa.N gonorrhoeae isolates inotapukirwa kune ese akaedzwa antimicrobials aive zvakanyanya (p <0.05) yakabatana neST 25 (87%).Zvimwe zvakakosha kushamwaridzana pakati pe ST neAMS zvaisanganisira: ST 3654 uye inotsaura ine zvishoma inhibitory concentrations ye ≥0.03 mg / L kusvika kuchizvarwa chechitatu ceph alosporins;ST 3711 (100%) uye TRNG;uye ST/boka 3654 (43%) uye chromosomal kuramba penicillin uye tetracycline.Mazhinji NG-MAST STs / mapoka ainyanyobatanidzwa neakasarudzika ane chromosomal kuramba tetracycline.Isolates inoshingirira ciprofloxacin (n=5) uye azithromycin (n=2) yakaonekwa sema STs ega ega.Kushamwaridzana kwakakosha kwakaonekwa pakati pe STS, zvepabonde uye zera remurwere, uye kugoverwa kwenharaunda uye kwenguva.Kushamwaridzana pakati peN gonorrhoeae AMS uye NG-MAST STs zvakaonekwa uye zvinogona kubatsira pakufanotaura nezveAMS munharaunda.Nekuti STs munyika dzakasiyana dzinosiyana zvakanyanya, kushandiswa kweNG-MAST yekufungidzira kweAMS pasi rose kunoda kumwe kudzidza.