Tazobactam Cas: 89786-04-9
Catalog Number | XD92373 |
Product Name | Tazobactam |
CAS | 89786-04-9 |
Molecular Formula | C10H12N4O5S |
Molecular Weight | 300.29 |
Storage Details | -15 kusvika -20 °C |
Harmonised Tariff Code | 29419000 |
Chigadzirwa Specification
Chitarisiko | Hupfu hwakachena kusvika kuchena |
Assay | 99% min |
Mvura | <0.5% |
Kutenderera chaiko | +127 kusvika +139 |
Heavy metals | <20ppm |
Residue paIgnition | <0.1% |
Zvose Zvisina Kuchena | <1.0% |
Tazobactam is penicillanic acid sulfone iyo yakafanana kuraira kune sulbactam.Iyo ine simba zvakanyanya β-lactamaseinhibitor kupfuura sulbactam uye ine zvishoma yakafara spectrumof chiitiko pane clavulanic acid.Iine antibacterialactivity isina simba.Tazobactam inowanikwa mu-fixed-dose, injectable cobinations nepiperacillin, yakakura-spectrum penicillin inosanganisira 8: 1 reshiyo yepiperacillin sodium kune tazobactamsodium nehuremu uye inotengeswa pasi pezita rekutengeserana rinonzi Zosyn. Pharmacokinetics yemishonga miviri yakafanana zvikuru.Vese vane hafu yeupenyu hupfupi (t1/2 ~1 awa), vane mapuroteni mashoma, vane ruzivo rwakanyanya rwemetabolism, uye vanoburitswa mafomu asingaite muweti munzvimbo dzakakwirira.
Zvinotenderwa zviratidzo zvepiperacillin–tazobactamcombination zvinosanganisira kurapwa kweappendicitis, postpartumendometritis, uye pelvic inflammatory disease inokonzerwa neβ-lactamase-inobudisa E. coli uye Bacteroides spp., ganda uye skin structure zvirwere zvinokonzerwa neβ-lactamase-producingS.aureus, uye mabayo anokonzerwa ne-β-lactamase-producingstrains yeH. influenzae.