Tiamulin 98% Cas: 125-65-5
| Catalog Number | XD91893 |
| Product Name | Tiamulin 98% |
| CAS | 125-65-5 |
| Molecular Formula | C22H34O5 |
| Molecular Weight | 378.5 |
| Storage Details | -20°C |
| Harmonised Tariff Code | 2918199090 |
Chigadzirwa Specification
| Chitarisiko | Upfu chena |
| Assay | 99% min |
| Melting point | 170-1710C |
| alpha | D24 +20° (c = 3 mu abs ethanol) |
| Boiling point | 482.8±45.0 °C(Zvakafanotaurwa) |
| density | 1.15±0.1 g/cm3(Zvakafanotaurwa) |
| solubility | DMSO:> 10mg/mL (inodziya) |
| pka | 12.91±0.10(Zvakafanotaurwa) |
| optical chiitiko | [α]/D +30 kusvika +40° (c=1; CH2Cl2) |
Pleuromutilin is diterpene inogadzirwa nemhando dzakasiyana-siyana dzebasidomycete, kunyanya genus Pleurotus, yakawanikwa muna 1951. Pleuromutilin imishonga ine simba uye inosarudza zvikuru inorwisa mabhakitiriya eGram positive, isina kupesana nekirasi yemishonga inorwisa mabhakitiriya nekuda kwemaitiro ayo akasiyana. zvechiito.Pleuromutilin inhibits protein synthesis nekusunga kune domain V ye23S rRNA uye izvi zvakakonzera kugadzirwa kweakawanda semi-synthetic analogues sechizvarwa chitsva chinorwisa mabhakitiriya, senge tiamulin uye retapamulin.
Pleuromutilins yakadai setiamulin uye valnemulin yakashandiswa kwenguva yakati mumishonga yemhuka yekurapa zvirwere zvenguruve.Munguva pfupi yadarika imwe semisynthetic pleuromutilin, retapamulin, yakaunzwa semushonga wepamusoro wezvirwere zveGram-positive muvanhu.Pleuromutilins inhibisa peptidyl transferase basa rebhakitiriya 50S ribosomal subunit nekusunga kune A saiti.
