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Aptasensor inoshanda yakagadziriswa umo graphene oxide (GO) yakashandiswa sechiratidzo kune ese electrochemical impedance spectroscopy uye electrochemiluminescence (ECL) chiratidzo chekugadzira.Iyo aptasensor yakagadzirwa nekuzvibatanidza yega ECL probe ye thiolated adenosine triphosphate binding aptamer (ABA) yakaiswa neRu complex (Ru(bpy)3(2+) derivatives) pamusoro pegoridhe nanoparticle (AuNP) yakagadziridzwa girazi kabhoni. electrode (GCE).ABA isina kufamba paAuNP yakagadziridzwa GCE inogona kushambadza GO nekuda kwekubatana kwakasimba kweπ-π pakati peABA negraphene oxide;ECL kudzimwa kweRu complex kunobva kwaitika nekuda kwekufambiswa kwesimba uye kuendesa maerekitironi, uye kuwedzera kukuru kweiyo electron transfer resistance (Ret) ye electrode.Ichiri pamberi pechinangwa cheadenosine triphosphate (ATP), ABA inofarira kuumba ABA-ATP bioaffinity complexes, iyo ine hukama husina simba kune graphene oxide uye inochengetedza graphene oxide kure ne electrode pamusoro, nokudaro inobvumira kuwedzera kwechiratidzo cheECL, uye pamwe chete nekuderera kweRet.Nekuda kweiyo ECL yakakwira yekudzima mashandiro, chimiro chakasiyana, uye zvemagetsi zvimiro zvegraphene oxide, iyo Ret uye ECL intensity inopesana nelogarithm yeATP concentration yaive mutsara muhupamhi kubva pa10 pM kusvika 10 nM ine ultra-low yekuona muganho we6.7 pM kusvika 4.8pm, zvichiteerana.Iyo aptasensor yakatsanangurwa yakaratidza yakanakisa kuberekana, kugadzikana, uye kwakasarudzika sarudzo, uye ATP inogona kunyatsosiyaniswa kubva kune yayo analogues.Zvinotonyanya kukosha, iyi inoshanda ECL aptasensor zano rakavakirwa paGO ichiita ese seye electrochemical uye ECL chiratidzo chechiratidzo chakajairwa uye chinogona kukwidziridzwa zviri nyore kune zvimwe zviitiko zvinosunga biological.