Mukuenderera mberi kwekutsvaga kwakachengeteka uye kunoshanda antidiabetic drug, marine algae inova yakakosha sosi inopa akawanda makomisheni eakakura ekurapa anogona.Alpha-amylase, alpha-glucosidase inhibitors, uye antioxidant makomisheni anozivikanwa kudzora chirwere cheshuga uye akatariswa zvakanyanya munguva pfupi yapfuura.Muchidzidzo chemazuva ano, mana akasvibira algae (Chaetomorpha aerea, Enteromorpha intestinalis, Chlorodesmis, uye Cladophora rupestris) akasarudzwa kuti aongorore alpha-amylase, alpha-glucosidase inhibitory, uye antioxidant basa mu vitro.The phytochemical constituents of all the extracts was qualitatives .Basa reAntidiabetic rakaongororwa nekudzivisa kukwanisa kwezvinyorwa zvinopesana nealpha-amylase uye alpha-glucosidase ne spectrophotometric assays.Basa reAntioxidant rakatemwa ne2,2-diphenyl-1-picrylhydrazyl, hydrogen peroxide (H2O2), uye nitric oxide scavenging assay.Gas chromatography-mass spectrometry (GC-MS) ongororo yakaitwa kuti zvionekwe komisheni huru ine chekuita neayo antidiabetic action.Pakati pezvakasiyana-siyana zvakaongororwa, chloroform inotorwa yeC. aerea (IC50 - 408.9 μg/ml) uye methanol yakatorwa yeChlorodesmis. (IC50 - 147.6 μg/ml) yakaratidza kudzivirira kunoshanda kurwisa alpha-amylase.Zvinyorwa zvakaongororwawo kuti alpha-glucosidase inhibition, uye hapana chiitiko chakaonekwa chakawanikwa.Methanol yakatorwa yeC. rupestris yakaratidza kucherechedzwa kwemahara radical scavenging basa (IC50 - 666.3 μg / ml), inoteverwa neH2O2 (34%) uye nitric oxide (49%).Kupfuurirazve, kunyoreswa kwemakemikari neGC-MS kwakaratidza kuvapo kwemahombe bioactive komisheni.Phenol, 2,4-bis (1,1-dimethylethyl) uye z, z-6,28-heptatriactontadien-2-one yainyanya kuwanikwa mumethanol extract yeC. rupestris uye chloroform extract yeC aerea.Zvigumisiro zvedu zvinoratidza iyo algae yakasarudzwa inoratidza inocherekedza alpha-amylase inhibition uye antioxidant basa.Nokudaro, maitiro emakemikari anoshanda uye ayo mu vivo assays achave akacherechedza.Mane algae akasvibirira akasarudzwa kuti aongorore alpha-amylase, alpha-glucosidase inhibitory, uye antioxidant basa in vitro C. aerea uye Chlorodesmis yakaratidza kuvharidzirwa kukuru kune alpha-amylase, uye C. rupestris yakaratidza kucherechedzwa kwemahara radical scavenging chiitikoHapana chakacherechedzwa chiitiko chakawanikwa chinopesana nealpha-glucosidaseGC-MS kuongororwa kweanoshanda anotora inoratidza kuvepo kwemakomisheni makuru ayo anopa nzwisiso pane antidiabetic uye antioxidant basa realgae idzi.Mapfupi anoshandiswa: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Gas chromatography-mass spectrometry.
