5-Iodo-2'-deoxycytidine CAS: 54-42-2 98-102% White crystalline powder
| Catalog Number | XD90562 |
| Product Name | 5-Iodo-2'-deoxycytidine |
| CAS | 54-42-2 |
| Molecular Formula | C9H11IN2O5 |
| Molecular Weight | 354.10 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29349990 |
Chigadzirwa Specification
| Chitarisiko | White crystalline powder |
| Assay | 99% |
| Kutenderera chaiko | +25 kusvika +30 |
| Heavy metals | <0.001% |
| Kurasika paKuomesa | <1.0% |
| Residue paIgnition | <0.3% |
Iyo inofungidzira 3D chimiro chekaviri-yakasungwa DNA inoita kuti ikwane setemplate yepasi-kumusoro dhizaini ye functionalized nucleic acid-based active sites.Isu pano tinoongorora mashandisirwo e14mer DNA duplex se scaffold yeiyo chaiyo uye inofanotaurwa chinzvimbo checatalytic functionalities.Zvichipa kubatanidzwa kwese kwese histidine-based imidazole boka muprotein recognition uye catalysis zviitiko, single histidine-like modified duplexes yakaongororwa.Kuisa histamine kuC5 yethymine base kuburikidza neamide bond, inobvumira kuchinjika chinzvimbo chemidazole basa mumugero mukuru.Kudyidzana pakati pe imidazole ne duplex uye simba rayo pa imidazolium pKaH inoongororwa nekuisa thymine imwe yakagadziridzwa panzvimbo ina dzakasiyana pakati pe 14mer double helix.Uchishandisa NMR uye isingadzoreki mamolecular dynamics, chimiro chechimiro chinosanganisira kuumbwa kwehydrogen bond pakati peimidazole neHoogste padivi pezvigadziko zve guanine zvezviviri zvakavakidzana zveGC base pairs zvinotangwa.Iyo motif inobatsira kudzikamisa kupesana nekunyunguduka kwekupisa kwe6 ° C uye yakakosha pakugadzirisa pKaH yeboka reimidazolium.Izvo zvakajairika maficha, zvinodikanwa uye generic hunhu hweiyo pKaH-inogadzirisa motif inotsanangurwa.
