Adenosine Cyclophosphate CAS: 60-92-4 99% White crystal powder
| Catalog Number | XD90570 |
| Product Name | Adenosine Cyclophosphate |
| CAS | 60-92-4 |
| Molecular Formula | C10H12N5O6P |
| Molecular Weight | 329.206 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29349990 |
Chigadzirwa Specification
| Chitarisiko | White crystal powder |
| Assay | 99% |
Iyo histamine H4 receptor (HRH4), yakawanikwa makore gumi nematatu chete apfuura, inoonekwa seanovimbisa mushonga wakanangana neallergy, kuzvimba, autoimmune kusagadzikana uye cancer, sezvinoratidzwa nehuwandu huri kuramba huchikura hwezvinyorwa zvesainzi uye mashandisirwo emvumo.Kunyangwe kuvepo kweHRH4 kwakaratidzwa mu testis, nzvimbo yayo chaiyo kana basa rayo harina kusimbiswa.Apa, takatsvaga kuona zvingangoitika zveHRH4 mukuronga kweLeydig cell function.Takatanga kuongorora kutaura kwayo muMA-10 Leydig tumor masero uye ndokuongorora mhedzisiro yevaviri HRH4 agonist pane steroidogenesis uye kuwanda.Takaona kuti HRH4 inoshanda inoratidzwa muMA-10 masero, uye kuti kushandiswa kwayo kunotungamirira kukudzivirira kweLH / munhu chorionic gonadotropin-induced cAMP kugadzirwa uye StarR protein expression.Uyezve, takaona kuderera kwekuwedzera kwesero mushure me24-h HRH4 agonist kurapwa.Isu takazoona nzvimbo dzeHRH4 kutaura mune yakajairwa rat tes tis, uye takaona HRH4 immunostaining muLeydig maseru emakonzo ane makore 7-240 mazuva, nepo 21-mazuva ekare airatidza HRH4 kutaura mumagametes echirume.Chekupedzisira, takaongorora mhedzisiro yeHRH4 activation pakuwanda kweakajairika gonzo uye rat Leydig cell tsika, uye zvese zvakaratidza kuve nyore kune anti-proliferative mhedzisiro yeHRH4 agonist.Tichifunga nezvekukosha kwehistamine (2-(1H-imidazol-4-yl) ethanamine) mumunhu (patho) physiology, kuenderera mberi kuedza kunonangana pakujekesa zvinhu zvinobuda zveHRH4 nemarunda ayo.Ichi chidzidzo chinoburitsa nzvimbo nyowani dzeHRH4 kutaura, uye inofanirwa kutariswa mukugadzirwa kwevanosarudza HRH4 agonist nekuda kwekurapa.
