Cytochrome C CAS: 9007-43-6 Tsvuku tsvuku kana yakasviba poda
| Catalog Number | XD90330 |
| Product Name | Cytochrome C |
| CAS | 9007-43-6 |
| Molecular Formula | C42H54FeN8O6S2 |
| Molecular Weight | 886.91 |
| Storage Details | -15 kusvika -20 °C |
| Harmonised Tariff Code | 35040090 |
Chigadzirwa Specification
| Chitarisiko | Tsvuku dzvuku kana hupfu hwakasvibira |
| Assay | 99% |
| pH | 5 - 7 |
| Iron | 0.40 - 0.48% |
| Kuchena | Zvishoma 90% |
| Residue paIgnition | Hukuru 1.5% |
| Unyoro | Max 6% |
| Kusabereka | Inopindirana nekuongorora sterility |
| Pyrogens | Free |
| Colorimetric Test | Positive |
| E. Coli | Absent |
| Salmonella Mhando | Absent |
| Solubility 10% mumvura | Zvakajeka nemuvara mutsvuku |
| Extinction value | Er/Eo:Min1.1 |
| Total Microbial Count cfu / g | Max 100 |
| Molds/Yeasts | Absent |
| Origin | Mwoyo webhiza |
Mabhuku ari kubuda anoratidza kuti bisphenol A (BPA), yakapararira endocrine kukanganisa kemikari, kana kuratidzwa kunoitika muhupenyu hwepakutanga, kunogona kuwedzera njodzi ye metabolic syndrome.Muchidzidzo ichi, takaongorora fungidziro yekuti kuratidzwa kweperinatal kuBPA kunofanotungamira vana kune chirwere chechiropa chine mafuta: kuratidzwa kwehepatic ye metabolic syndrome, uye nzira yayo inogona.Ane nhumbu Wistar makonzo aipihwa neBPA (40μg/kg/zuva) kana mota panguva yekuzvitakura uye kuyamwisa.Chiropa histology, biochemical analysis, transcriptome, uye mitochondrial basa yakaongororwa mumwana wechirume mushure mekusununguka 3, 15 uye mavhiki e26.Pamasvondo e3 ezera, kusagadzikana kwechiropa morphology uye basa hazvina kuonekwa muBPA-yakafumurwa vana, asi kuderera kwemitochondrial breathing complex (MRC) basa (I uye III) uye kuchinja kukuru mukutaura kwemajini kunobatanidzwa mumitochondrial fatty acid metabolism yaiva. zvakacherechedzwa zvichienzaniswa nezvinodzora.Pamasvondo gumi nemashanu, micro-vesicular steatosis muchiropa, up-re gulated genes inobatanidzwa mu lipogenesis nzira, kuwedzera ROS chizvarwa uye Cytc kusunungurwa kwakaonekwa muBPA-yakafumurwa vana.Zvadaro, kuwanda kwemafuta kuunganidza muchiropa uye serum yakakwirira ALT yakaonekwa muBPA-yakafumurwa vana pamavhiki e26.Mukutarisa kwenguva refu, basa rehepatic mitochondrial rinosanganisira basa reMRC, kugadzirwa kweATP, ROS chizvarwa uye mitochondrial membrane inogona kuwedzera zvishoma nezvishoma muBPA-yakafumurwa vana.Perinatal BPA kuratidzwa kunobatsira mukugadzirwa kwehepatic steatosis muvana vemakonzo, iyo inogona kupindirana kuburikidza nekukanganiswa kwehepatic mitochondrial basa uye up-regulated hepatic lipid metabolism.
