Yakananga Blue Cas: 314-13-6
| Catalog Number | XD90533 |
| Product Name | Direct Blue |
| CAS | 314-13-6 |
| Molecular Formula | C34H24N6Na4O14S4 |
| Molecular Weight | 960.81 |
| Storage Details | Ambient |
| Harmonised Tariff Code | 32129000 |
Chigadzirwa Specification
| Chitarisiko | Upfu dema |
| Assay | 99% |
| Kurasika paKuomesa | 10% max |
| Solubility pa 0.1% mumvura | Yakajeka mhinduro yebhuruu |
| Wavelenght ye max absorption | 605 - 613nm |
| Chaiyo Absorbance (E1% / 1cm) | 800min |
Vascular hyperpermeability inobatsira mukurwara mukuzvimba.Nzira dzazvino dzekuita mu vivo ongororo yepermeability yakavakirwa pakuwedzera kweEvans Blue (EB)-yakasungwa albumin inonetsa uye kazhinji inoshaya manzwiro.Isu takagadzira inoveli infrared fluorescence (IRF) nzira yekuyera yeEB-albumin extravasation kuti iverenge vascular permeability mumurine modhi.Vascular permeability inokonzerwa ne endotoxaemia yakaongororwa kune yese nhengo dzakasimba, huropi, ganda uye peritoneum ne IRF uye yechinyakare absorbance-based kuyerwa kweEB mune zvinyorwa zvematishu.Organ IRF yakawedzera mutsara nekuwedzera kuwanda kweiyo intravenous EB (2.5-25 mg/kg).Tissue IRF yainyanya kunzwisiswa kuunganidzwa kweEB kana ichienzaniswa neyekunyudza-yakavakirwa nzira.Saizvozvo, misiyano yevascular permeability uye organ EB kuunganidza pakati pe lipopolysaccharide-yakarapwa uye saline-yakagadziriswa mbeva yaiwanzove yakakosha payakaongororwa neIRF-based kucherechedzwa asi kwete nekunyura-kwakavakirwa kuona.EB yakaonekwa munhengo dzese dze353 dzakaongororwa neIRF asi mu67% (239/353) yenhengo dzakaongororwa neabsorbence-based methodology, zvichiratidza kunzwisiswa kwakavandudzika kwekuonekwa kweEB munhengo dzine IRF.Kusiyana neizvi, EB muplasma mushure mekutonga kweEB yakayerwa nyore nyore nenzira mbiri dzine kuwirirana kwepamusoro pakati penzira mbiri (n = 116, r2 = 0.86).Kuwanda kweorgan-specific EB-IRF misiyano nekuda kwe endotoxin yaive yakakwana apo IRF yakaenzaniswa pakati pembeva dzakafananidzwa nehuremu, murume kana mukadzi, uye zera, uye nekugadziriswa kwakakodzera kwehuremu hwenhengo uye EB plasma concentrations.Zvikuru, EB-IRF nzira inosiya nhengo dzakasimba kune inotevera histopathology.Muchidimbu, EB-IRF ibhuku, rinonzwa zvakanyanya, rinokurumidza, uye riri nyore nzira yehuwandu hweEB munhengo dzakasimba dzekurapa maringe nemakonzo.
