L-Aspartic acid CAS: 56-84-8 99% White powder
| Catalog Number | XD90315 |
| Product Name | D-Aspartic asidhi |
| CAS | 56-84-8 |
| Molecular Formula | C4H7NO4 |
| Molecular Weight | 133.10 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29224985 |
Chigadzirwa Specification
| Chitarisiko | Upfu chena |
| Assay | 99% |
| Giredhi | USP34 |
| Kutenderera chaiko | +24,5 kusvika +26 |
| Tungamira | <0.0005% |
| Kurasika paKuomesa | <0.25% |
| Residue paIgnition | <0.1% |
Iyo EAAT2 glutamate transporter, inoverengera> 90% yehippocampal glutamate inotora.Kunyangwe EAAT2 ichinyanya kuratidzwa mune astrocytes, ~10% yeEAAT2 mamorekuru anowanikwa mumaaxon terminals.Kunyangwe iyo yakaderera nhanho yeEAAT2 kutaura mune glutamatergic terminals, kana hippocampal zvimedu zvakanyudzwa neyakadzikira d-aspartate (an EAAT2 substrate), axon terminals inounganidza d-aspartate nekukurumidza seastroglia.Izvi zvinoreva kusawirirana kusingatsananguriki pakati pekugoverwa kweEAAT2 protein uye EAAT2-mediated yekufambisa basa.Imwe pfungwa ndeyekuti (1) heteroexchange yemukati substrate nekunze substrate inokurumidza zvakanyanya kupfuura kutora mambure uye (2) materminals anofarira heteroexchange nekuda kwemazinga akakwira emukati glutamate.Nekudaro, parizvino hazvizivikanwe kana heteroexchange uye kutora zvine mareti akafanana kana akasiyana.Kuti tigadzirise nyaya iyi, takashandisa hurongwa hwakagadziridzwa kuti tienzanise mwero wehukama hwemaitiro maviri mumakonzo nemakonzo.Kutora mambure kwakanzwisiswa kune shanduko mune membrane inogona uye yakakurudzirwa nekunze permeable anions mukubvumirana nekuvapo kweiyo isina kubatanidzwa anion conduction.Nekushandisa iyo yekupedzisira, isu tinoratidza zvakare kuti mwero weheteroexchange unoenderanawo nekugona membrane.Pamusoro pezvo, data redu rinowedzera kuratidza kuvepo kwe sodium leak muEAAT2.Nekubatanidza zvitsva zvakawanikwa mune yedu yapfuura modhi ye glutamate kutora neEAAT2, isu tinofanotaura kuti voltage senitivity yekuchinjana inokonzerwa nevoltage-inotsamira yechitatu Na(+) inosunga.Kupfuurirazve, zvese zvedu zviedzo uye zviyedzero zvinoratidza kuti hukama hwemambure ekutora uye heteroexchange inofananidzwa muEAAT2.
