Rapamycin kubva kuStreptomyces hygroscopicus CAS:53123-88-9 Ichena kusvika kune-chena-chena kana yero crystalline poda
Catalog Number | XD90356 |
Product Name | Rapamycin kubva kuStreptomyces hygroscopicus |
CAS | 53123-88-9 |
Molecular Formula | C51H79NO13 |
Molecular Weight | 914.17 |
Storage Details | -20 °C |
Harmonised Tariff Code | 2942000000 |
Chigadzirwa Specification
Assay | 99% |
Chitarisiko | Ichena kusvika kuchena-chena kana yero yecrystalline poda |
Rapamycin, mushonga wakaratidzwa kuti uwedzere hupenyu mumakonzo, unodzivisa chinangwa cherapamycin (TOR) nzira, nzira huru inodzora sero kukura uye simba resimba.Izvo zvave zvichifungidzirwa kuti rapamycin uye kurambidzwa kwekudya (DR) kunowedzera hupenyu kuburikidza nenzira dzakafanana / nzira.Tichishandisa microarray analysis, takaenzanisa zvinyorwa zvewhite adipose tissue kubva kumakonzo akadyiswa rapamycin kana DR-kudya kwemwedzi mitanhatu.Multidimensional scaling uye heatmap kuongororwa kwakaratidza kuti rapamycin yakanga isina mhedzisiro pane transcriptome kana ichienzaniswa neDR.Semuenzaniso, zvinyorwa zvitanhatu chete zvakashandurwa zvakanyanya ne rapamycin apo mbeva dzakadyiswa DR dzakaratidza kuchinja kukuru mune zvinyorwa zve1000.Tichishandisa huchenjeri nzira yekuongorora, takaona kuti stearate biosynthesis uye circadian rhythm siginecha yakashandurwa zvakanyanya neDR.Zvatinowana zvinoratidza kuti DR, asi kwete rapamycin, ine mhedzisiro pane transcriptome yeadipose tissue, zvichiratidza kuti izvi zviviri manipulations zvinowedzera hupenyu kuburikidza nenzira dzakasiyana / nzira.