(S)-2-Amino-4-hydroxybutanoic acid Cas: 672-15-1
| Catalog Number | XD90286 |
| Product Name | (S) -2-Amino-4-hydroxybutanoic acid |
| CAS | 672-15-1 |
| Molecular Formula | C4H9NO3 |
| Molecular Weight | 119.11916 |
| Storage Details | Ambient |
| Harmonised Tariff Code | 29225000 |
Chigadzirwa Specification
| Assay | 99% |
| Chitarisiko | Upfu chena |
Chidzidzo chezvino chinotsanangura nzira yakapusa uye inoshanda uchishandisa yakakwira performance liquid chromatography (HPLC) yakasanganiswa nefluorescence kutariswa kweiyo kinetic parameters ye glutamate kutora mune tsinga tishu.Retinal tissue yakawanikwa kubva ku7-day-old chickens yakanyungudutswa nehuwandu hunozivikanwa hwe glutamate (50-2000 μM) kwemaminetsi gumi, uye mazinga e-o-phtaldehyde (OPA) -derivatized neurotransmitter mu incubation medium akayerwa.Nekuongorora mutsauko pakati pekutanga uye kwekupedzisira kusungirirwa kwe glutamate mukati, saturable uptake mechanism yakaratidzwa (K (m) = 8.2 uye V (max) = 9.8 nmol / mg protein / min).Ichi chiyero chainyanya kuenderana nesodium- uye tembiricha, ichitsigira zvakasimba kuti magadzirirwo ekudzikira anotorwa nevatakuri vepamusoro-soro.Kuwedzerwa kune izvi, zvigumisiro zvedu zvakaratidzawo kuti zinc chloride (inhibitor ye glutamate / aspartate transporters) yakamutsa kuderera-kunotsamira kuderera mu glutama te uptake, zvichiratidza kujeka kwemaitiro edu.Pakazere, iro basa razvino rinoratidzira imwe nzira yekuongorora glutamate kutora mutsinga matishu uchishandisa HPLC.Iyi nzira inogona kunge iri chishandiso chakakosha chezvidzidzo zvine chekuita nekufananidzwa kweminiti shanduko mukutakura kweglutamate zvine chekuita nekukuvara kwepakati tsinga.
