Streptavidin kubva kuStreptomyces avidinii CAS:9013-20-1
Catalog Number | XD90329 |
Product Name | Streptavidin kubva kuStreptomyces avidinii |
CAS | 9013-20-1 |
Molecular Formula | C14H17BrClNO2S |
Molecular Weight | 378.71 |
Storage Details | -15 kusvika -20 °C |
Harmonised Tariff Code | 35040090 |
Chigadzirwa Specification
Chitarisiko | Upfu chena |
Assay | 99% |
Zvekutsvaga kushandiswa chete, kwete zvekushandisa kwevanhu | tsvakurudzo inoshandiswa chete, kwete yekushandiswa kwevanhu |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) ine alkyne boka yakaratidzwa kuva mechanic-based target-specific irreversible inhibitor ye sialidases.Iyo ester-protected analog DFSA (PDFSA) ndeye membrane-permeable precursor yeDFSA yakagadzirirwa kushandiswa mumaseru mapenyu, uye yakaratidzwa kuumba covalent adducts nehutachiona, mabhakitiriya, uye sialidases yevanhu.Iyo fluorosialyl-enzyme adduct inogona kubatanidzwa neazide-annexed biotin kuburikidza nekudzvanya maitiro uye inowonekwa neiyo streptavidin-chaiwo masaini ekuzivisa.Liquid chromatography-mass spectrometry/mass spectrometry ongororo pazvimedu zvetryptic peptide inoratidza kuti 3-fluorosialyl moiety inoshandura tyrosine zvisaririra zve sialidases.DFSA yakashandiswa kuratidza hutachiona hwefuruwenza uye kuongororwa kwehutachiwana kune anti-fluenza drug oseltamivir acid, nepo PDFSA yakashandiswa in situ imaging yekuchinja kwekuita sialidase mumasero mhenyu.