Tetracycline hydrochloride CAS: 64-75-5 99% Yero crystalline upfu
| Catalog Number | XD90366 |
| Product Name | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| Molecular Formula | C22H24N2O8 · HCl |
| Molecular Weight | 480.90 |
| Storage Details | -15 kusvika -20 °C |
| Harmonised Tariff Code | 29413000 |
Chigadzirwa Specification
| Mhedziso | Inoenderana neBP2013, EP7, USP38 |
| Heavy metals | <0.005% |
| Kusachena Kumwechete | <0.1% |
| Identification | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Kurasika paKuomesa | <2.0% |
| Residual solvent | n-Butanol <3000ppm |
| Assay | BP2013/EP7 99% |
| Sulfated Ash | <0.5% |
| Specific optical rotation | -240 kusvika -255 ° |
| Potency | USP 38: > 900ug/mg |
| Zvose Zvisina Kuchena | <5% |
| Chitarisiko | Yellow crystalline powder |
| 4-epianhydrotetracycline | <2% |
| Microbial miganhu | Zvinoenderana |
| 4-Epiteracycline | <3% |
| Anhydrotetracyoline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Residual Solvent | <100ppm |
Kuvandudzwa kweantimicrobial resistance kwakapihwa kuwandisa uye kusashandisa zvisizvo zveantimicrobial agents.Staphylococci chikamu chezvakajairwa flora asi zvakare anogona hutachiona hutachiona hwakave hwakanyanya kurwisa kune akawanda anozivikanwa maantibiotic.Resistance in coagulase negative staphylococci (CoNS) inokurudzirwa kuti ishanduke nekuda kwekusarudzwa kwakanaka kunotevera kurapwa kwemishonga inorwisa mabhakitiriya.Chidzidzo ichi chakaongorora kuvepo kwezvipfumbamwe zvinonyanya kushandiswa antimicrobial agents muweti yevanhu kubva kuvarwere vari kunze muzvipatara zviviri muGhana maererano neCoNS kuramba.Weti neCons dzakatorwa (n = 246 uye n = 96 zvichiteerana) kubva kuvarwere muzvipatara zviviri muGhana.CoNS yakaonekwa pachishandiswa Gram staining, coagulase test, uye MALDI-TOF/MS, uye antimicrobial susceptibility kune 12 inowanzoshandiswa antimicrobials yakagadziriswa ne disk diffusion.Zvakare nzira yekuongorora yakagadziridzwa kuti iongororwe yezvipfumbamwe zvinonyanya kushandiswa antimicrobial agents muGhana nekushandisa solid-ph ase extraction pamwe neHPLC-MS/MS vachishandisa electron spray ionization.Iyo yakanyanya kuwanda kwekupokana neCoNS yakaonekwa kune penicillin V (98%), trimethoprim (67%), uye tetracycline (63%).S. haemolyticus ndiyo yaive yakazviparadzanisa nevamwe (75%), ichiteverwa neS. epidermidis (13%) uye S. hominis (6%).S. haemolyticus yaivewo mhando yemhando yairatidza kupikisa kwakanyanya (82%).69% yeCoNS yakasarudzika yaive yakawanda isingaite zvinodhaka (≧ 4 mishonga inorwisa mabhakitiriya) uye 45% yeCoNS yaidzivirira methicillin.Mishonga inorwisa utachiona yakaonekwa muchikamu che64% chezvakaongororwa weti samples (n = 121) apo maantimicrobial aiwanzoonekwa aive ciprofloxacin (30%), trimethoprim (27%), uye metronidazole (17%).Zvakanyanya kuwanikwa zvechidzidzo ichi ndezvokuti kuwanda kwemishonga inorwisa mabhakitiriya muweti yainyanya kudarika kushandiswa kwakaitwa nevarwere uye kupararira kweS.
