Thiamphenicol Cas: 15318-45-3
Catalog Number | XD92378 |
Product Name | Thiamphenicol |
CAS | 15318-45-3 |
Molecular Formula | C12H15Cl2NO5S |
Molecular Weight | 356.22 |
Storage Details | Ambient |
Harmonised Tariff Code | 29414000 |
Chigadzirwa Specification
Chitarisiko | White crystalline powder |
Assay | 99% min |
Melting Point | 163°C - 167°C |
Heavy metals | ≤10ppm |
Kurasika paKuomesa | ≤1.0% |
Specific optical rotation | -21° - 24° |
Chloride | ≤0.02% |
Thiamphenicol imishonga inorwisa mabhakitiriya chloramphenicol yakakura, iyo inoshanda zvakanyanya kumabhakitiriya egiremu-negative kupfuura mabhakitiriya egiramu-positive.Patembiricha yemumba, ichena kusvika kuchena-chena crystalline poda kana kristaro, inogona kukurumidza uye kunyudzwa zvachose nemuromo wekutonga, uyezve inoburitswa zvakanyanya muiyo prototype kubva muweti yemetabolism.Inoshandiswa kuchipatara kurapwa kwekufema, weti, chiropa uye gallbladder, typhoid uye kumwe kuvhiyiwa kwematumbo, gynecology uye ENT zvirwere.Kunyanya muzvirwere zvinyoro zvinonyanya kushanda.Iine chimiro chakafanana chemakemikari ne chloramphenicol.Yayo methyl sulfone yakatsiva nitro ye chloramphenicol, iyo yakaderedza huturu hwayo, uye mu vivo basa rayo rinorwisa utachiona rakasimba ka 2.5-5 kupfuura chloramphenicol.Kune mabhakitiriya egiremu, akadai se streptococcus pneumoniae uye hemolytic streptococcus, ane antibacterial effect yakasimba kwazvo, ukuwo kune giremu-negative bacteria, seNeisseria gonorrhoeae, meningococcus, lung Bacteroides, E. coli, Vibrio cholerae, Shigella nefuruwenza, inewo yakasimba antibacterial effect.Kune anaerobic bacteria, Rickettsia uye amoeba, ine antibacterial mhedzisiro mune imwe nhanho.Iine imwechete antimicrobial mechanism ine chloramphenicol, iyo inonyanya kurambidza kuumbwa kweprotein yebhakitiriya.Mushonga uyu unotorwa nekukurumidza nemuromo wekutonga, izvo zvinosvika peak yeropa mukati memaawa maviri.Hhafu yehupenyu hwayo maawa mashanu, iyo yakareba kupfuura chloramphenicol.Utachiona hune hupikisi hwakakwana pairi uye chloramphenicol, nepo mabhakitiriya ane chimwe chinhu chinopikisa-chinopikisa uye tetracycline.
Thiamphenicol ine zvakare yakasimba immunosuppressive mhedzisiro, inova yakanakisa immunosuppressant.Maitiro ayo ekuita ane akasiyana zvakanyanya nemamwe ma immunosuppressive agents.Iyo immunosuppressive mhedzisiro yakapetwa kakawanda kupfuura iyo chloramphenicol.Inogona kunge iri seyainoshanda yekuwedzera yekuchinjisa maitiro uye yekuvhiya allogeneic transplantation.