Vancomycin hydrochloride Cas: 1404-93-9 Ichena inenge chena kana kuti tani kusvika kuhupfu hwepingi
| Catalog Number | XD90197 |
| Product Name | Vancomycin hydrochloride |
| CAS | 1404-93-9 |
| Molecular Formula | C66H76Cl3N9O24 |
| Molecular Weight | 1485.7145 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29419000 |
Chigadzirwa Specification
| Mvura | NMT 5.0% |
| Heavy metals | NMT 30ppm |
| pH | 2.5 - 4.5 |
| Bacterial endotoxins | NMT 0.33EU/mg yeVancomycin |
| Kujeka Kwemhinduro | Zvakajeka |
| Chitarisiko | Ichena, inenge chena, kana kuti tani kusvika kuhupfu hwepingi |
| Vancomycin B | NLT 85% |
| Muganho we monodechlorovancomycin | NMT 4.7% |
| Assay (microbial, anhydrous base) | NLT 900ug/mg |
1.Kuitika kwehutachiona hweStaphylococcus aureus husingaregi kunharaunda inowanikwa munharaunda huri kuwedzera nekukurumidza.Kurapa kunobudirira kwagara kuchisanganisira kukurumidza kuomeswa uye kutonga kwemishonga inorwisa mabhakitiriya.Chidzidzo ichi chakagadzirirwa kuona kushanda kwe empiric therapy mukurapa hosha dzemaoko.Kuedza kusingatarisirwi kwakaitwa paLevel I County hospital.Varwere vane utachiona hwemaoko vakagamuchira empiric intravenous vancomycin pakupinzwa kana intravenous cefazolin.Migumisiro yakateverwa nekushandiswa kwehutachiwana hwehutachiona, mhinduro yakakodzera yekiriniki, uye urefu hwekugara.Mari-inoshanda yakaverengerwa uchishandisa mutengo wakakwana kumurwere wega wega mumapoka maviri.Nhamba dzekuongorora dzakaitwa.Varwere makumi mana nevatanhatu vakanyoreswa muchidzidzo.Makumi maviri nemana akaverengerwa ku cefazolin (52.2 muzana) uye 22 (47.8 muzana) kune vancomycin.Pakanga pasina mutsauko wenhamba pakati pemutengo wekurapa (p <0.20) kana kureba kwekugara (p <0.18) pakati pemapoka.Varwere vakarongedzerwa ku cefazolin vaive nemitengo yepamusoro yekurapa kana ichienzaniswa nevarwere vaive vakasarudzika kune vancomycin (p <0.05).Varwere vane hutachiona hwakanyanya hwakanyanya kudhura hunoreva mari yekurapa (p <0.0001) uye kureba kureba kwekugara (p = 0.0002).Pedyo nekupera kwechidzidzo, chiitiko chemunharaunda-yakatorwa methicillin-resistant S. aureus pavanyori ' County hospital yakaonekwa iine 72 muzana, izvo zvakaita kuti chidzidzo chimiswe nguva isati yakwana nedare rekuongorora remasangano nekuda kwekuwanda kwezviitiko. kurambidza kumwe kurongeka.Kurapwa kwakakodzera kwekutanga kwemethicillin-resistant S. aureus hakusati kwanyatsozivikanwa.Hapana mutsauko mumhedzisiro uchishandisa cefazolin maringe nevancomycin semumiriri wekutanga wakaonekwa.
2.Nekuvandudzwa kwekuporesa maronda kuburikidza nekushandisa intravenous prophylactic antibiotics uye kugadziriswa kwehutano, postoperative elbow zvirwere zvave zvisinganyanyi kuitika asi zvichiri kuitika mune mamwe maitiro ekuvhiyiwa kwegokora.Chinangwa chechidzidzo ichi chaiva chekuongorora kuchengetedzwa uye kushanda kweprophylactic kushandiswa kwevancomycin munzvimbo yekushanda kuti kuderedze kuitika kwehutachiona mushure mekusunungurwa kwepashure kwemashure akaoma. period yakaitwa.Muboka rinodzora (varwere ve93), prophylaxis iri nyore neyakajairwa intravenous antibiotics yakaitwa;muboka revancomycin (varwere ve179), vancomycin powder yakashandiswa zvakananga muronda risati ravharwa pamwe chete neyakajairwa intravenous prophylaxis.Mushure mekutevera kweinenge mwedzi 6, boka rekutonga rakaonekwa kuti rine zvirwere zve6 (6.45%; chivimbo; kupindirana: 2.40% -13.52%) zvichienzaniswa neasina (0%; nguva yekuvimba: 0-2%.04%) muboka revancom ycin, iro raive mutsauko wakakosha (P = .0027).Hapana migumisiro yakaipa yakanyorwa kubva pakushandiswa kwakananga kwevancomycin powder.Kushandiswa kwepanzvimbo yevancomycin powder inogona kuva nzira inovimbisa yekudzivirira zvirwere zvegorofu mushure mekusunungurwa kwegorofu kune varwere vane mushure mekuoma kwegorofu.
