5-Sulfosalicylic acid dihydrate Cas: 5965-83-3 Ichena kusvika kunze-chena kristaro
| Catalog Number | XD90230 |
| Product Name | 5-Sulfosalicylic acid dihydrate |
| CAS | 5965-83-3 |
| Molecular Formula | C7H10O8S |
| Molecular Weight | 254.215 |
| Storage Details | Ambient |
| Harmonised Tariff Code | 29182900 |
Chigadzirwa Specification
| Sulfate | 5.5% yakawanda |
| Unyoro | 22% max |
| Chitarisiko | Ichena kusvika kune-chena kristaro |
| Total acid | 99 - 104% |
| Assay | 99% |
Polycations inoongororwa sevatakuri kuendesa therapeutic nucleic acids.Mapolycations akajairwa pharmacological inert ine basa rega rekuunza mishonga yekurapa.Ichi chidzidzo chinoshuma synthesis ye self-immolative polycation (DSS-BEN) yakavakirwa pa polyamine analogue mushonga N(1),N(11)-bisethylnorspermine (BENSpm).Iyo polycation yakagadzirirwa kushanda zvakapetwa senge gene kutakura mutakuri uye prodrug yakanangana ne dysregulated polyamine metabolism mugomarara.Tichishandisa musanganiswa weNMR uye HPLC, tinosimbisa kuti iyo self-immolative polycation inopinda intracellular degradation mumubereki mushonga BENSpm.Iyo yakaburitswa BENSpm inopedza masero emasero espermidine uye spermine uye inokwidza polyamine catabolic enzymes spermine/spermidine N (1) -acetyltransferase (SSAT) uye spermine oxidase (SMO).Iwo akagadzirwa mapolycation anoumba mapolyplexes ane DNA uye anobatsira kutapurirana kwakanaka.Kutora mukana wekugona kweBENSpm kukurudzira maseru ekenza kuTNFα-induced apoptos, isu tinoratidza kuti DSS-BEN inosimudzira basa rekuuraya sero reTNFα gene therapy.Izvo zvakashumwa zvakawanikwa zvinosimbisa DSS-BEN seyakaviri-inoshanda dhizaini system inogona kuunza jini rekurapa uye kugadzirisa mhedzisiro yegene therapy semhedzisiro ye intracellular degradation yeDSS-BEN kuenda kuBENSpm uye inotevera inobatsira yeBENSpm pane dysregulated polyamine. metabolism mugomarara.
