Doxycycline hyclate CAS: 24390-14-5 99% Yellow crystalline powder
| Catalog Number | XD90368 |
| Product Name | Doxycycline hyclate |
| CAS | 24390-14-5 |
| Molecular Formula | C22H24N2O8·HCl·0.5C2H6O·0.5H2O |
| Molecular Weight | 512.94 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29413000 |
Chigadzirwa Specification
| Kusachena A | <2% |
| KusachenaB | <2% |
| Kutenderera chaiko | -105 kusvika -120 |
| pH | 2-3 |
| Kusachena C | <0.5% |
| KusachenaD | <0.5% |
| Kurasika paKuomesa | 1.4-2.8% |
| Assay | 99% |
| Residue paIgnition | <0.4% |
| Absorbtivity | 300-335 |
| Chero kumwe kusachena kumwe chete | <0.5% |
| Chitarisiko | Yellow crystalline powder |
| Kusachena F | <0.5% |
| KusachenaE | <0.5% |
| Ethyl Doro | 4.5 - 6% |
| Kutora kusachena | <0.07% |
Kuumbwa kweBiofilm pane mazino abutment kunogona kutungamirira kune peri-implant mucositis uye inotevera peri-implantitis.Zvirwere izvi zvinorapwa nemishonga inorwisa mabhakitiriya yakadai sedoxycycline (Doxy).Pano takashandisa nzira ye electrochemical ye cathodic polarization kupfekedza Doxy pamusoro pekunze kwemazino abutment material.Iyo Doxy-yakavharwa pamusoro yakaratidza kuputika kuburitswa muphosphate-buffered saline panguva yekutanga 24 h.Nekudaro, huwandu hwakakosha hweDoxy hwakaramba huri pamusoro kweinenge mavhiki maviri kunyanya pa5 mA-3 h sampu ine yakakwira Doxy huwandu, zvichiratidza zvese zvekutanga uye zvenguva refu bacteriostatic mukana weiyo yakavharwa.Kemikari yepamusoro yakaongororwa ne x-ray photoelectron spectroscopy uye yechipiri ion mass spectrometry.Surface topography yakaongororwa nemunda emission scanning electron microscopy uye blue-light profilometry.Kurebesa polarization nguva kubva 1 h kusvika 5 h uye yakakwirira ikozvino density kubva 1 kusvika 15 mA cm (-2) yakakonzera kuwanda kweDoxy pane surfa ce.Iyo yepamusoro yakafukidzwa nedhizaini yeDoxy isingasviki 100 nm pasina shanduko huru mutopography.Iyo antibacterial properties yeDoxy-coated surface yakaongororwa ne biofilm uye planktonic kukura assays uchishandisa Staphylococcus epidermidis.Doxy-coated samples yakaderedza zvese biofilm kuunganidza uye planktonic kukura mune muto tsika, uye zvakare inhibited kukura kwebhakitiriya pamahwendefa eagar.Iyo antibacterial effect yaive yakasimba kune sampuli dze5 mA-3 h yakavharwa nehuwandu hwepamusoro hweDoxy kana ichienzaniswa neye 1 mA-1 h.Saizvozvo, iyo abutment nzvimbo yakavharwa neDoxy ine mukana wekudzivirira bhakitiriya colonization kana yaiswa pamuromo wemuromo.Doxy-coating inogona kunge iri nzira inoshanda yekudzora peri-implant mucositis uye kudzivirira kufambira mberi kwayo kuita peri-implantitis.
