Products

Iyo europium(III) uye terbium(III) yakaoma, zvinoti [Eu(dpq)(DMF)2(NO3)3] (1), [Eu(dppz)2(NO3)3] (2), [Tb(dpq) )(DMF)2Cl3] (3), uye [Tb(dppz)(DMF)2Cl3] (4), apo dipyrido[3,2-d:2',3'-f]quinoxaline (dpq mu1 ne3) , dipyrido [3,2-a: 2',3'-c] phenazine (dppz mu2 uye 4) uye N, N'-dimethylformamide (DMF) yakave yakaparadzaniswa, inoratidzwa kubva kune yavo physicochemical data, luminescence zvidzidzo uye kuwirirana kwavo. neDNA, serum albumin protein uye photo-induced DNA cleavage basa inodzidzwa.I-X-ray crystal structures ye-complexes 1-4 inoratidza discrete mononuclear Ln (3+)-based structures.Iyo Eu(3+) mu[Eu(dpq)(DMF)2(NO3)3] (1) uye [Eu(dppz)2(NO3)3] (2) se[Eu(dppz)2(NO3)3 ]·dppz (2a) inotora gumi-yakarongeka bicapped dodecahedron chimiro chine bidentate N,N-donor dpq ligand, maviri DMF uye matatu NO3(-) anions mu1 uye maviri bidentate N,N-donor dppz ligands uye matatu NO3( -) anions mu 2. Complexes 3 uye 4 inoratidza nomwe-yakabatana mono-capped octahedron chimiro apo Tb(3+) ine bidentate dpq/dppz ligands, maviri DMF uye matatu Cl(-) anions.Iwo macomplexes anopenya zvakanyanya muzvisikwa achiratidza kushanda zvakanaka kwefoto-kunakidzwa kwesimba rekutamisa kubva kudpq/dppz antenna kuenda kuLn(3+) kuti ibudise mamiriro ekugara kwenguva refu ekufarisa kwehunhu f → f shanduko.Iyo nguva-yakagadziriswa luminescence spectra yemacomples 1-4 inoratidza yakamanikana mabhendi ekuburitsa ayo anonzi (5)D0 → (7)F(J) uye (5)D4 → (7)F(J) ff shanduko yeEu(3) +) uye Tb(3+) ions zvichiteerana.Huwandu hwemukati-sphere mvura mamorekuru (q) yakatemwa kubva ku luminescence lifetime zviyero muH2O uye D2O inosimbisa ligand-exchange reactions nemvura mune mhinduro.Iwo macomplexes anoratidza akakosha kusunga propensity kune iyo CT-DNA ichipa inosunga inoramba ichikosha muhuwandu hwe1.0 × 10(4) -6.1 × 10(4) M(-1) muhurongwa 2, 4 (dppz)> 1, 3 (dpq).DNA inosunga data inoratidza DNA groove inosunga pamwe nechikamu chekudyidzana chimiro chezvakaoma.Ese macomplexes anoratidzawo kusunga propensity (K(BSA) ~ 10(5) M(-1)) kune bovine serum albumin (BSA) protein.Kusimba kweiyo nguva-gated luminescence spectral mabhendi inosimudzira zvakanyanya nekuwedzera kweDNA kusungirirwa muaqueous buffer medium nekuda kwekusimuka kwemvura yakasungwa pakubatana neDNA, nokudaro kuderedza kusinga-radiative kudzimwa kuburikidza neOH oscillator.Complexes 1-4 zvine hunyanzvi hwekutsemura supercoiled (SC) ds-DNA kune yayo nicked denderedzwa (NC) fomu pakusangana neUV-A mwenje we365 nm kuburikidza nekugadzirwa kwe singlet oxygen ((1)O2) uye hydroxyl radicals (HO˙) se iyo reactive okisijeni mhando pane micromolar concentrations pasi pemamiriro emuviri.