Pyridoxal-5'-phosphate monohydrate CAS: 41468-25-1 99% Yakavharwa-chena kune chiedza yellow powder
| Catalog Number | XD90390 |
| Product Name | Pyridoxal-5'-phosphate monohydrate |
| CAS | 41468-25-1 |
| Molecular Formula | C8H10NO6P·H2O |
| Molecular Weight | 265.16 |
| Storage Details | 2 kusvika ku8 °C |
| Harmonised Tariff Code | 29362500 |
Chigadzirwa Specification
| Heavy metals | 20ppm max |
| Yese plate count | 1000 cfu/g max |
| E.Coli | Negative |
| Salmonella | Negative |
| Kurasika paKuomesa | 10.0% max |
| Staphylococcus aureus | Negative |
| Assay | 99% |
| Chitarisiko | Kuchena-kuchena kusvika kuhupfu yeyero |
| Yeast & Mold Count | 100 cfu/g max |
| Zuva rekugadzira | TBC |
| Coliform | Negative |
| Pyridoxine (HPLC) | 0.01 % max |
| PH(0.25% ag Solution) | 2.6-3.0 |
Kubudirira kugadzirisa myelin muCNS yakakura kunoda kugadzirwa kwakasimba uye nenguva yemapuroteni emyelin kuti abudise miyelin sheaths itsva.Izvo zviri pasi pekutonga maitiro uye yakaoma mamorekuru hwaro hwemyelin regeneration, zvisinei, zvinoramba zvisinganzwisisike.Pano, isu tinoongorora basa reERK MAP kinase kusaina mune iyi maitiro.Kubviswa kweErk2 kubva kumasero emutsara we oligodendrocyte kwakakonzera kunonoka kudzoreredza mushure mekukuvadzwa kwedemyelinating kune mukuru mouse corpus callosum.Kugadziriswa kwakanonoka kwakaitika semugumisiro wekukanganisa kwakananga mukushandurwa kweprotein ye myelin, MBP.Mukusavapo kweERK2, kushandiswa kweribosomal protein S6 kinase (p70S6K) uye chinangwa chayo chepasi, ribosomal protein S6 (S6RP), yakakanganiswa panguva yakaoma apo premyelinating oligodendrocytes yakanga ichishandura kune masero akakura anokwanisa kugadzira mitsva yemyelin sheaths.Nekudaro, isu takatsanangura hukama hwakakosha pakati peERK MAP kinase inosaina cascade uye tra-nslational michina yakanyatso mu remyelinating oligodendrocytes in vivo.Iyi mhedzisiro inoratidza basa rakakosha reERK2 mukududzira kutonga kweMBP, puroteni yemyelin inoratidzika yakakosha pakuita kuti chizvarwa chakakodzera chemyelin sheaths chinotevera kukuvara kwedemyelinating muCNS yakakura.
