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tRNA ndiyo yakanyanya kugadziridzwa kirasi yeRNA mhando, uye gadziridzo dzinowanikwa mutRNAs kubva kune zvese zvipenyu zvakaongororwa.Zvisinei nekusiyana kwakasiyana-siyana kwemakemikari maumbirwo uye kuvapo kwavo mumatRNA akasiyana, achiitika munzvimbo dzakasiyana muTRNA, nzira dzebiosynthetic dzehuwandu hwemagadzirirwo etRNA dzinosanganisira nhanho yemethylation.Zvichangoburwa zvakawanikwa zvakaratidza kuoma kusati kwamboitika mumatanho ekugadzirisa etRNA, kudzora uye basa ravo, zvichiratidza kuti imwe neimwe yakagadziridzwa nucleoside mutRNA inogona kuve neyayo chaiyo basa.Nekudaro, muzvirimwa, ruzivo rwedu pamusoro pebasa remunhu ega tRNA gadziriso uye kuti inodzorwa sei ishoma.Muchidzitiro chemajini chakagadzirirwa kuona zvinhu zvinogadzirisa kuramba kwechirwere uye activation yezvidziviriro muArabidopsis, takaona SUPPRESSOR OF CSB3 9 (SCS9).Mhedzisiro yedu inoratidza SCS9 encodes a tRNA methyltransferase inoyananisa iyo 2'-O-ribose methylation yemhando dzakasarudzwa dzetRNA muantico don loop.Aya ma SCS9-mediated tRNA magadzirirwo anowedzera panguva yekutapukirwa nebhakitiriya pathogen Pseudomonas syringae DC3000, uye kushaikwa kweiyo tRNA gadziriso, sezvakaonekwa mune scs9 mutants, inokanganisa zvakanyanya kudzivirira kwechirimwa kurwisa the pathogen imwechete pasina kukanganisa salicylic acid (SA) kusaina. nzira iyo inogadzirisa mhinduro dzezvirwere zvemuviri.Mhedzisiro yedu inotsigira modhi inopa kukosha kune kudzora kweimwe tRNA gadziriso yekusimudza inoshanda immune system muArabidopsis, uye nekudaro inowedzera repertoire yezvikamu zvemamorekuru zvakakosha pamhinduro yekurwisa chirwere.